Clinical implications and management of drug|drug interactions ...

Pharmacokinetic drug-drug interaction and their implication in ...

In particular, poly-therapy increases the complexity of therapeutic management and thereby the risk of clinically important DDIs, which can both induce the ...

Drug Interactions—Principles, Examples and Clinical Consequences

Drug interactions can have desired, reduced or unwanted effects. The probability of interactions increases with the number of drugs taken.

Clinical implications and management of drug-drug interactions ...

SUMMARY. Drug-drug interactions with HAART therapy often complicate treatment of psychiatric illnesses in HIV-infected patients. Of the ...

Clinically Relevant Drug-Drug Interactions in Primary Care - AAFP

Drug interactions based on altered metabolism are mostly attributable to effects on cytochrome P450 (CYP450) isozymes. Inhibition or induction ...

Drug Interactions: Scientific and Clinical Principles - ACCP

... drug interactions and their impact on patients ... essary; and monitor the patient for improved outcomes or potential adverse effects if treatment discontinuation.

Clinically Significant Drug Interactions - AAFP

A large number of drugs are introduced every year, and new interactions between medications are increasingly reported.

Recommendations for Management of Clinically Significant Drug ...

A drug-drug interaction (DDI) is a pharmacokinetic or pharmacological influence of 1 medication on another that differs from the known or anticipated ...

Knowing how clinicians make real-world decisions about drug-drug ...

Drug-drug interactions causing adverse effects are common and can cause significant patient harm and even death.

Drug-Drug Interactions between Antiretrovirals and Other Drugs | NIH

The magnitude and significance of interactions are difficult to predict when several drugs with competing metabolic pathways and drug transporter systems are ...

Drug Interactions - Merck Manual Professional Edition

Drug interactions are changes in a drug's effects due to recent or concurrent use of another drug or drugs (drug-drug interactions), ingestion of food (drug- ...

Drug interaction and its implication in clinical practice and ... - njppp

Adequate knowledge of drug DIs will enable the health-care professionals to individualize the patient treatment in order to get maximum therapeutic benefit.

The impact of disease‐drug interactions on drug development and ...

Early identification and proper management of disease-drug interaction would facilitate drug development and improve clinical practice. From ...

[PDF] Pharmacokinetic drug-drug interaction and their implication in ...

Pharmacokinetic drug-drug interaction and their implication in clinical management · Caterina Palleria, A. di Paolo, +5 authors. L. Gallelli · Published in ...

Drug-Drug Interactions and the Clinical Tolerability of Colchicine ...

Our study highlights the challenges with evaluation of drug-related adverse effects and drug-drug interactions. Drug-drug interaction studies ...

Drug-disease and drug-drug interactions: systematic examination of ...

In this review of NICE clinical guidelines, potentially serious drug-drug interactions were relatively common among recommendations for each of ...

Pharmacokinetic Drug-Drug Interactions with Drugs Approved by the ...

The mechanism(s) and clinical relevance of these interactions were characterized based on information available in the new drug application ...

Cognitive task analysis of clinicians' drug–drug interaction ...

Background Drug–drug interactions (DDIs) are common and can result in patient harm. Electronic health records warn clinicians about DDIs via alerts, but the ...

Drug interaction management | International Journal of Clinical ...

Although thousands of articles on drug interactions have been published and numerous computerized screening systems have been developed, patients continue ...

Classification of drugs for evaluating drug interaction in drug ...

The classification would be informative for designing clinical studies during the development stage, and the appropriate management of drug interactions in ...

Cardio-Oncology Drug Interactions: A Scientific Statement From the ...

Interpatient variability can influence a DI given the potential impact of age, sex, genetics, and comorbid conditions on drug handling.

Essence of Anesthesia Practice

Book by Lee A. Fleisher and Michael Roizen