Coagulome and the tumor microenvironment

Coagulome and the tumor microenvironment: an actionable interplay

Human tumors often trigger a hypercoagulable state that promotes hemostatic complications, including venous thromboembolism.

Coagulome and the tumor microenvironment: an actionable interplay

Abstract. Human tumors often trigger a hypercoagulable state that promotes hemostatic complications, including venous thromboembolism. The ...

The role of coagulome in the tumor immune microenvironment

The rising incidence and persistent thrombosis in multiple cancers including those that are immunosuppressive highlight the need for ...

The role of coagulome in the tumor immune microenvironment

We focus on the role of coagulation factors in priming a suppressive TIME and the huge potential of existing anticoagulant drugs in the clinical settings of ...

Coagulome and the tumor microenvironment: an actionable interplay

cancer treatment. 37. (104 words). 38. 39. 40. 41. 42. Key words. 43. 44. Coagulome; Venous thromboembolism; Tumor microenvironment; Anticoagulants; Biomarkers.

The breast cancer coagulome in the tumor microenvironment and its ...

We aimed to broadly investigate the breast tumor coagulome and its relation to prognosis, treatment response to chemotherapy, and the tumor microenvironment.

The coagulation-related genes for prognosis and tumor ...

Emerging evidence suggests that coagulation is closely linked to the tumor microenvironment (TME) [15]. The TME is composed of various cell ...

Coagulome and the tumor microenvironment: an actionable interplay

- The coagulation cascades exert multiple direct and indirect effects on cancer cells and the components of the tumor microenvironment, both within and outside ...

The Tumor Coagulome as a Transcriptional Target and a Potential ...

The concept of the tumor « coagulome » refers to the repertoire of tumor-expressed genes that locally regulate coagulation and fibrinolysis [4]. Systems biology ...

A pan-cancer analysis of the human tumor coagulome and its link to ...

It is also unclear whether the coagulome is associated with specific characteristics of the tumor microenvironment (TME). We aimed to address ...

(PDF) Coagulome and tumor microenvironment: impact of ...

Single cell transcriptomic analysis of brain tumours reveals the coexistence of multiple coagulant mechanisms associated with different cancer ...

The role of coagulome in the tumor immune microenvironment - OUCI

Saidak, A pan-cancer analysis of the human tumor coagulome and its link to the tumor immune microenvironment, Cancer Immunol. Immunother., № 70, с. 923

Coagulome and the tumor microenvironment: an actionable interplay

(DOACs), are available for the treatment of thrombosis in cancer patients [1,2]. The coagulation system has traditionally been depicted as a ...

Unraveling breast cancer prognosis: a novel model based on ...

Recent studies (Tinholt et al., 2024) have revealed the crucial role of coagulation-related genes in the tumor microenvironment of breast cancer ...

impact of oncogenes, cellular heterogeneity and extracellular vesicles

Coagulome and tumor microenvironment: impact of oncogenes, cellular heterogeneity and extracellular vesicles. Authors. Nadim Tawil · https://orcid.org/0000-0003 ...

Full article: Targeting coagulation to unlock antitumor immunity?

We recently applied systems biology and genomics to explore the regulation of the tumor immune microenvironment by coagulation.

Molecular Landscape of the Coagulome of Oral Squamous Cell ...

We aimed to study the coagulome of Oral Squamous Cell Carcinoma (OSCC) and examine its link to the tumor microenvironment (TME).

The breast cancer coagulome in the tumor microenvironment and its ...

We aimed to broadly investigate the breast tumor coagulome and its relation to prognosis, treatment response to chemotherapy, and the tumor microenvironment.

Characterization of coagulation-related gene signature to predict ...

The correlation between risk score and clinicopathological characteristics, tumor microenvironment (TME), and immunotherapy was further analyzed ...

Tissue factor in tumor microenvironment: a systematic review

... coagulation cascade and thrombosis. Laboratory and clinical evidence showed the deviant expression of TF in several cancer systems and its tumor ...