Combined measurement of plasma cell proliferative and apoptotic ...

We assessed plasma cell proliferation (by propidium iodide index, PC-PI) and apoptosis (by annexin-V index PC-AI) for the estimation of overall survival ...

Combined Measurement of Plasma Cell Proliferation and Apoptosis ...

Plasma cell proliferation and apoptosis represent key factors in multiple myeloma (MM) expansion and tumor survival.

Our results suggest that combined measurement of plasma cell proliferation and apoptosis creates a unique strong prognostic factor based on growth ...

Monitoring of plasma cell proliferative and apoptotic indices in the ...

In a group of 310 patients with multiple myeloma (MM) we assessed the proliferative (PC-PI) and apoptotic indices (PC-AI). Patients were divided according ...

Combining Measurements of Plasma Cell Apoptosis and ...

The proliferative rate of plasma cells, measured in terms of % plasma cells labeled by bromodeoxyuridine (BrdU) using slide based fluorescence ...

Combined measurement of plasma cell proliferative and apoptotic ...

Request PDF | Combined measurement of plasma cell proliferative and apoptotic index in multiple myeloma defines patients with good and poor prognosis | We ...

Measurement of apoptosis and proliferation of bone marrow plasma ...

The proliferative rate of malignant plasma cells, as measured by the plasma cell labelling index (PCLI), is an important prognostic factor in multiple ...

Proliferation to Apoptosis Tumor Cell Ratio as a Biomarker to ... - MDPI

Proliferation and apoptosis of neoplastic cells are prognostic biomarkers in plasma cell neoplasms (PCNs). The prognostic capacity of proliferation to ...

[PDF] Proliferation to Apoptosis Tumor Cell Ratio as a Biomarker to ...

47 References · Combined measurement of plasma cell proliferative and apoptotic index in multiple myeloma defines patients with good and poor prognosis. · Plasma ...

Combined Measurement of Plasma Cell Proliferation and Apoptosis ...

Combined Measurement of Plasma Cell Proliferation and Apoptosis in Multiple Myeloma. Konference: 2009 51th ASH Annual Meeting – účast ČR. Kategorie ...

Measurement of apoptosis and proliferation of bone marrow plasma ...

Lastly, since a combination of both the labelling and apoptosis indices may better predict net tumour growth, we developed a plasma cell growth index that ...

Proliferation to Apoptosis Tumor Cell Ratio as a Biomarker to ... - OUCI

... Neoplasma, № 53, с. 213; Minarik, Combined measurement of plasma cell proliferative and apoptotic index in multiple myeloma defines patients with good and ...

Study on Tim3 Regulation of Multiple Myeloma Cell Proliferation via ...

Figure 5 Cell apoptosis in the RPMI-8226 and U266 cell lines detected by flow cytometry using annexin V-Fluorescein isothiocyanate (FITC)/ ...

Analysis of the anti-proliferative and the pro-apoptotic efficacy of Syk ...

Multiple myeloma (MM) is a clonal B cell malignancy characterized by proliferation of malignant plasma cells in the bone marrow.

(PDF) Proliferation to Apoptosis Tumor Cell Ratio as a Biomarker to ...

Proliferation and apoptosis of neoplastic cells are prognostic biomarkers in plasma cell neoplasms (PCNs). The prognostic capacity of ...

Understanding heterogeneity of human bone marrow plasma cell ...

The DNA fragmentation factor (DFFA) and apoptotic membrane blebbing gene ROCK1 were also upregu- lated.61–64 The PB stage also had a high ...

Patient-specific computational models predict prognosis in B cell ...

Simulations predicted adverse impact on clinical prognosis when combinations of mutations induced both anti-apoptotic (AA) and pro-proliferative ...

Plasma Cell Neoplasms (Including Multiple Myeloma) Treatment ...

Plasma cell neoplasms (including multiple myeloma) treatment include observation, chemotherapy, radiation, stem cell rescue, targeted, ...

Survival of Long-Lived Plasma Cells (LLPC) - Frontiers

Durable humoral immunity is dependent upon the generation of antigen-specific antibody titers, produced by non-proliferating bone marrow resident long-lived ...

Plasma Cell Survival Is Mediated by Synergistic Effects of Cytokines ...

Purified plasma cells (100 cells/well) were cultured together ... In accordance, it has been shown that stromal cells can prevent apoptosis of plasma cells ...