Combining Measurements of Plasma Cell Apoptosis and ...

Combining Measurements of Plasma Cell Apoptosis and Proliferation in Multiple Myeloma Identifies Patients with Poor Survival. ... Blood (2005) 106 ...

Conclusion: The measurement of plasma cell apoptosis has prognostic value in patients with MM. More importantly, we have shown that by combining measures of two ...

Combined measurement of plasma cell proliferative and apoptotic ...

We assessed plasma cell proliferation (by propidium iodide index, PC-PI) and apoptosis (by annexin-V index PC-AI) for the estimation of overall survival ...

Combined Measurement of Plasma Cell Proliferation and Apoptosis ...

Plasma cell proliferation and apoptosis represent key factors in multiple myeloma (MM) expansion and tumor survival.

Measurement of apoptosis and proliferation of bone marrow plasma ...

The proliferative rate of malignant plasma cells, as measured by the plasma cell labelling index (PCLI), is an important prognostic factor in multiple ...

Proliferation to Apoptosis Tumor Cell Ratio as a Biomarker to ... - MDPI

Proliferation and apoptosis of neoplastic cells are prognostic biomarkers in plasma cell neoplasms (PCNs). The prognostic capacity of proliferation to ...

Apoptosis Kits for Flow Cytometry - Accurate Detection Tools

Combining measurement of changes in the plasma membrane, necrosis, and changes in the mitochondrial membrane. Annexin Buffers. Annexin V fluorescent ...

Combination Treatment with Cold Physical Plasma and Pulsed ...

The plasma exposure time was 40 s, and the electric field strength was 0.9 kV/cm. Percentages of viable, early, and late apoptotic, as well as necrotic cells ...

Combination therapy of cold atmospheric plasma (CAP ... - Nature

Flow cytometry was used to assess the number of cells in the three distinct phases of the cell cycle (G1, S, and G2/M). Cells that undergo ...

Understanding heterogeneity of human bone marrow plasma cell ...

... plasma cells results in resistance to apoptosis ... 98. Wittkowski, K.M. ∙ Lee, E. ∙ Nussbaum, R. ... Combining several ordinal measures in ...

The Endoplasmic Reticulum Is a Key Component of the Plasma Cell ...

PC undergoing spontaneous cell death present some of the typical features of apoptosis, such as condensation of chromatin to the periphery of ...

Progressive differentiation toward the long-lived plasma cell ...

Koike et al. employ a time-stamping method for plasma cells and measure the decay of the homeostatic plasma cells with distinct isotypes, ...

Fc RIIb mediates apoptosis of plasma cells - University of Cambridge

The affinity of the anti-NP IgG present in the serum, as determined by measurement of binding to differentially haptenated NP conjugates, was not altered (data ...

Therapeutic effect and mechanism of ibrutinib combined with ...

Multiple myeloma (MM), a B-cell hematologic malignancy characterized by abnormal infiltration of terminally differentiated plasma cells in bone marrow, is the ...

Combination of chemotherapy and physical plasma elicits ... - Nature

The observed synergistic effects in tumor cells was due to enhanced intracellular doxorubicin accumulation via upregulation of the organic ...

About Multiple Myeloma

One caveat is that these measurements include both the normal (made by normal plasma cells) and abnormal amount of heavy chain (i.e., IgG, IgA made by myeloma ...

Activated PI3Kδ signals compromise plasma cell survival via limiting ...

Activation of PI3Kδ signaling in B cells impairs autophagy, leading to increased ER stress and plasma cell death in an mTORC1-dependent ...

Plasma Cell Survival Is Mediated by Synergistic Effects of Cytokines ...

These results strongly support the concept that plasma cell survival depends on niches in which a combination of specific signals, including IL-5, IL-6, stromal ...

Understanding heterogeneity of human bone marrow plasma cell ...

Hom et al., Maturation of human long- lived plasma cells results in resistance to apoptosis ... Combining several ordinal measures in clinical ...

Annexin V Staining | Thermo Fisher Scientific - US

In this combination, cells that are only annexin V-positive and therefore have intact plasma membranes, are demonstrably apoptotic. We offer a range of kits ...