Comparative gene expression profile of chronic myeloid leukemia ...

Amongst the differentially-expressed genes correlating with imatinib resistance, several suggest the activation of alternative pathway(s) that maintain ...

We describe here whole-genome expression analysis of imatinib-sensitive and -resistant cells derived from the original KCL22 line, using Affymetrix microarray ...

Comparative Gene Expression Analysis Reveals Similarities and ...

Chronic myeloid leukemia (CML) is a blood cancer with a very good long-term prognosis for the majority of patients.

Comparison of microRNA Expression Profile in Chronic Myeloid ...

Chronic myeloid leukemia (CML) results from a translocation between chromosomes 9 and 22, which generates the Philadelphia chromosome. This forms BCR/ABL1, ...

Comparative gene expression analysis of a chronic myelogenous ...

Chronic myelogenous leukemia (CML) is a disease characterized by a reciprocal translocation between chromosomes 9 and 22 resulting in a fusion gene which is ...

Comparative gene expression profile of chronic myeloid leukemia ...

RESULTS: We detected differential expression of 39 genes that correlate with the imatinib-resistant phenotype. The resistant cells overexpress several genes ...

Gene expression profiling of chronic myeloid leukemia with variant t(9

In this study, we performed gene expression microarray analysis to compare CML patients bearing variant rearrangements and those with classic t(9;22)(q34;q11).

Global gene expression profiles of hematopoietic stem and ...

We also determined the genomic changes in both normal and CML progenitor cells under culture conditions, and found that several genes involved ...

Comparative gene expression profile of chronic myeloid leukemia ...

Request PDF | Comparative gene expression profile of chronic myeloid leukemia cells innately resistant to imatinib mesylate | Resistance to ...

Integrating genetic and epigenetic factors in chronic myeloid ...

Chronic myeloid leukemia (CML) is a clonal disorder of the hematopoietic stem cell compartment defined and driven by the BCR-ABL1 gene ...

Comparative Gene Expression Analysis Reveals Similarities and ...

Comparative Gene Expression Analysis Reveals Similarities and Differences of Chronic Myeloid Leukemia Phases. ... profiles of the three CML ...

(PDF) Comparative Gene Expression Analysis Reveals Similarities ...

We performed an in-depth bioinformatics analysis of publicly available gene expression profiles of the three CML phases. Pairwise comparisons ...

Chronic myeloid leukemia (CML) is a myeloproliferative disease resulting from the clonal expansion of pluripotent hematopoietic stem cells [1,2, ...

Gene expression changes associated with progression and ... - PNAS

We used DNA microarrays to compare gene expression in 91 cases of CML in chronic (42 cases), accelerated (17 cases), and blast phases (32 cases).

Comparative Gene Expression Analysis Reveals Similarities and ...

Chronic myeloid leukemia (CML) is a slowly progressing blood cancer that primarily affects elderly people. Without successful treatment, CML progressively ...

Gene Expression Profiling in CD34+ Cells of Patients with Chronic ...

Chronic myeloid leukaemia (CML) is a malignant, clonal and proliferative disease originating from haematopoietic stem cells. The aim of this ...

Gene expression profiling of imatinib and PD166326-resistant CML ...

Chronic myeloid leukemia (CML) is a hematopoietic stem cell disease characterized by an acquired cytogenetic abnormality resulting from the ...

Comparative Gene Expression Analysis Reveals Similarities and ...

Comparative Gene Expression Analysis Reveals Similarities and Differences of Chronic Myeloid Leukemia Phases. ... gene expression profiles of the three CML ...

Comparative gene expression profile of chronic myeloid leukemia ...

Heidari N., Vosoughi T., Mohammadi Asl J., Saki Malehi A., Saki N. Q2. Taylor & Francis. Biomarkers , 2018 ...

Genome-wide comparison of the transcriptomes of highly enriched ...

BCR-ABL gene rearrangement and expression of primitive hematopoietic progenitors in chronic myeloid leukemia. ... Differential proteomic profile ...