Comprehensive analysis of DNA damage repair in squamous cell ...

Aims: Defective components resulting from DNA damage and repair mechanisms have been found to be underlying causes that affect the development ...

Our study established two subtypes of SCC based on DNA damage repair, which may help to predict prognosis and determine the most suitable treatment for SCC ...

A Comprehensive Analysis of Alterations in DNA Damage Repair ...

Esophageal squamous cell cancer (ESCC) is a common malignancy with a poor 5-year overall survival in China. Altered DNA damage repair (DDR) ...

Comprehensive analysis of DNA damage repair in squamous cell ...

Request PDF | Comprehensive analysis of DNA damage repair in squamous cell carcinoma subtypes | Aims Defective components resulting from DNA damage and ...

DNA damage repair profiling of esophageal squamous cell ...

DNA damage repair (DDR) is a critical process that maintains genomic integrity and plays essential roles at both the cellular and organismic ...

Comprehensive analysis of DNA damage repair in squamous cell ...

List of references · Okonkwo, Heterocyclic analogs of sulforaphane trigger DNA damage and impede DNA repair in colon cancer cells: interplay of HATs and HDACs, ...

DNA damage repair: historical perspectives, mechanistic pathways ...

In the following years, extensive evidence obtained using many new methods developed from the study of DDR processes indicated that DNA repair, ...

A novel DNA damage repair gene-related prognostic model for ...

This study aimed to investigate the potential prognostic value of DNA damage repair genes (DDRGs) in esophageal squamous cell carcinoma ...

The Prognostic Value of the DNA Repair Gene Signature in Head ...

Head and neck squamous cell carcinoma (HNSCC) is a type of tumor that originates from the squamous epithelium of the head and neck areas, ...

Corrigendum to "Comprehensive analysis of DNA damage repair ...

... Comprehensive analysis of DNA damage repair subtypes of squamous cell carcinoma" [Life Sci. 278 (2021) 119559 | Find, read and cite all the ...

Comprehensive analysis of DNA damage repair deficiency in ...

Genomic instability is a crucial feature of cancer. DDR defects, mismatch repair (MMR) defects for instance, will lead to microsatellite ...

A score of DNA damage repair pathway with the predictive ability for ...

DNA damage repair (DDR) is critical in maintaining normal cellular function and genome integrity and is associated with cancer risk, ...

Cisplatin benefit is predicted by immunohistochemical analysis of ...

Here predictive utility of DNA repair enzymes co-segregates with SCC histology, focusing their predictive value to this histological subclass of NSCLC. Distinct ...

DNA damage repair gene signature model for predicting prognosis ...

Lung squamous cell carcinoma (LUSC) is prone to metastasis and likely to develop resistance to chemotherapeutic drugs. DNA repair has been ...

Identification of a DNA damage repair gene‐related signature for ...

DNA damage repair (DDR) plays a role in the tumorigenesis and progression of lung squamous cell carcinoma (LUSC), but the predictive value of ...

Implications for drug development and - Annals of Oncology

Comprehensive analysis of DNA damage repair deficiency across. 10,613 pan-cancer patients: Implications for drug development and therapy. W. Xie, J. Zhao, X ...

Genomic and Molecular Landscape of DNA Damage Repair ...

DNA damage repair (DDR) pathways modulate cancer risk, progression, and therapeutic response. We systematically analyzed somatic alterations ...

DNA repair phenotype and cancer risk: a systematic review ... - Nature

The overall pooled OR (95% CI) for DNA repair deficiency and cancer risk was 2.92 (2.49, 3.43) (Fig. 2). We saw significant heterogeneity across ...

A Comprehensive Analysis of Alterations in DNA Damage Repair ...

A Comprehensive Analysis of Alterations in DNA Damage Repair Pathways Reveals a Potential Way to Enhance the Radio-Sensitivity of Esophageal Squamous Cell ...

The effects of altered DNA damage repair genes on mutational ...

Esophageal carcinoma (EC) is the seventh most common and the sixth most lethal cancer worldwide. Esophageal squamous cell carcinoma (ESCC), the ...