Comprehensive assessment of cellular senescence in intestinal ...

Therefore, evaluating the involvement of genes related to cellular senescence in UC intestinal inflammation and immunity helps elucidate the ...

Comprehensive analysis for cellular senescence-related ...

In malignancies, cellular senescence is critical for carcinogenesis, development, and immunological regulation. Patients with acute myeloid ...

Algorithmic assessment of cellular senescence in experimental and ...

In the first phase, we combine the measurement of lysosomal and proliferative features with the expression of general senescence-associated genes to validate ...

A new face of old cells: An overview about the role of senescence ...

Cellular senescence is a pivotal factor contributing to aging and the pathophysiology of age-related diseases. Despite the presence of inflammation and ...

Comprehensive assessment of cellular senescence in the tumor ...

Abstract. Cellular senescence (CS), a state of permanent growth arrest, is intertwined with tumorigenesis. Due to the absence of specific ...

The connection between aging, cellular senescence and gut ...

The intricate interplay between cellular senescence and alterations in the gut microbiome emerges as a pivotal axis in the aging process, ...

The Role of Cellular Senescence in the Gastrointestinal Mucosa

Cellular senescence is emerging as a widespread cellular end point in GI oncology and its importance is becoming increasingly recognized as an ...

Cellular senescence in gastrointestinal diseases: from pathogenesis ...

Cellular senescence is induced in response to various stresses and can either prevent or fuel disease and tumorigenesis.

Guidelines for minimal information on cellular senescence ...

An important layer of complexity in senescence assessment in situ/in vivo is the sheer heterogeneity of senescence phenotypes across different ...

A strategy for the treatment of gastrointestinal cancer - Frontiers

A new approach to treat GI cancer is the use of the tumor suppressive effect of cellular senescence, avoiding the tumor promoting effect, improving the ...

A guide to assessing cellular senescence in vitro and in vivo

In an effort to better identify this complex state, and given that a universal marker has yet to be identified, a general set of hallmarks ...

Guidelines for minimal information on cellular senescence ...

Therefore, comprehensive analysis of senescent cells using various markers is required. Skeletal muscle. Muscle is a complex tissue composed of ...

Comprehensive Analysis of Cellular Senescence-Related Genes in ...

Cellular senescence is a tumor suppressive response in which the cell cycle is in a state of permanent arrest and can inhibit tumor cell ...

Cellular Senescence, Inflammation, and Cancer in the ... - MDPI

The incidence of gastrointestinal tract (GI) diseases, including cancers increases with age, partially due to the accumulation of senescent ...

Emerging Interrelationship Between the Gut Microbiome and ...

It is thus evident that intestinal epithelial, as well as stem cells, exhibit age-dependent cellular senescence which can contribute to known ...

Overall, we performed a comprehensive analysis of cellular senescence-associated genes using a bioinformatics approach, revealing their ...

The cellular senescence score (CSS) is a comprehensive biomarker ...

The cellular senescence score (CSS) is a comprehensive biomarker to predict prognosis and assess senescence and immune characteristics in hepatocellular ...

Identification of Senescence-Related Subtypes, the Development of ...

Cellular senescence is associated with tumorigenesis, and the subtype and prognostic signatures of senescence-related genes (SRGs) in the tumor microenvironment ...

ELMO1 ameliorates intestinal epithelial cellular senescence via ...

To assess the contribution of cellular senescence in IBD-related fibrostrictured, we compared the cellular senescence gene list (1,100 genes) ...

Intestinal stem cells acquire premature senescence and ... - Aging-US

senescence in damage bearing ISCs and both these outcomes have the potential for functional alterations and oncogenic transformations in gastrointestinal tissue ...