Conformational IgE Epitope Mapping of Der p 2 and the Evaluations ...

Epitope mapping of Der p 2, a clinically important dust-mite allergen is the first step in designing immunotherapy hypoallergen vaccine ...

Conformational IgE Epitope Mapping of Der p 2 and - ProQuest

Two mutants with consistent low IgE binding, K96A and E102A, were subsequently evaluated as hypoallergen candidates. IgG antibodies raised in mice against both ...

(PDF) Conformational IgE Epitope Mapping of Der p 2 and the ...

Two mutants with consistent low IgE binding, K96A and E102A, were subsequently evaluated as hypoallergen candidates. IgG antibodies raised in ...

Human IgE monoclonal antibody recognition of mite allergen Der p ...

Key amino acids forming the IgE epitope on Der p 2 were identified. Mutation of these residues ablated their functional ability to cross-link ...

Conformational IgE Epitope Mapping of Der p 2 and the Evaluations ...

AbstractEpitope mapping of Der p 2, a clinically important dust-mite allergen is the first step in designing immunotherapy hypoallergen vaccine candidates.

A human IgE antibody binding site on Der p 2 for the design of a ...

Conformational IgE epitope mapping of Der p 2 and the evaluations of two candidate hypoallergens for immunotherapy. Sci Rep 8: 3391. [DOI] [PMC free article] ...

Mapping Human Monoclonal IgE Epitopes on the Major Dust Mite ...

The analysis showed that the Der p 2 methyls responded to both remote conformational ... Conformational IgE epitope mapping of Der p 2 and the evaluations of two ...

Analysis of the IgE-epitope of Der f 2, a major mite allergen, by in ...

Antigenic and structural analysis of group II allergens (Der f II and Der p II) from house dust mite (Dermatophagoides spp.) J. Allergy clin. Immun., 83 (1989), ...

IgE-binding residues analysis of the house dust mite allergen Der p 23

Conformational IgE epitope mapping of Der p 2 and the evaluations of two candidate hypoallergens for immunotherapy. Sci. Rep. 8, 3391 (2018) ...

A Human IgE Antibody Binding Site on Der p 2 for the Design of a ...

Conformational IgE epitope mapping of Der p 2 and the evaluations of two candidate hypoallergens for immunotherapy. Sci. Rep. 8. : 3391 . Google Scholar.

Conformational IgE Epitope Mapping of der p 2 and the Evaluations ...

Conformational IgE Epitope Mapping of der p 2 and the Evaluations of Two Candidate Hypoallergens for Immunotherapy. 10.1038/s41598-018-21792-1. Saved in: ...

Epitope mapping of the Dermatophagoides pteronyssinus house ...

Our results suggest that the increased conformational stability of Der p 2 depressed the IgE production in mice. These findings should provide a milestone ...

... IgE epitopes using anti-Der p 21 peptide antibodies (Table 2). ... Figure 3 presents a summary of the IgE epitope mapping obtained for Der p 5 and ...

IgE and IgG 4 antibodies from patients with mite allergy recognize ...

Several groups reported epitope mapping of IgE antibody but not of IgG or IgG subclass antibodies in Der p 2. OBJECTIVE: The purpose of this study was to ...

IgE Epitopes of the House Dust Mite Allergen Der p 7 Are ... - Frontiers

Peptide-specific antibodies were used to inhibit allergic patients` IgE binding to Der p 7 by ELISA for mapping of IgE epitopes. Results: rDer p 7 showed high ...

Mapping Human Monoclonal IgE Epitopes on the Major Dust Mite ...

A new hybridoma technology using human B cells from house dust mite-allergic patients was used to identify four Der p 2-specific hIgE mAbs.

Epitope mapping of the house‐dust‐mite allergen Der p 2 by means ...

Recombinant Der p 2, expressed in the baker's yeast Saccharomyces cerevisiae. was used as a tool to determitie IgE- and monoclonal antibody ...

Precision engineering for localization, validation, and modification of ...

Conformational IgE epitopes of peanut allergens Ara h 2 and Ara h 6. Clin ... Mapping human monoclonal IgE epitopes on the major dust mite allergen Der p 2.

Identification of immunodominant IgE binding epitopes of Der p 24, a ...

Thus far, B cell epitopes have been identified for only group 1, 2, 3, 7, 11, 13, 23 and 33 HDM allergens [16,17,18,19,20,21]. Traditionally, ...

Identification of immunodominant IgE epitopes of the major house ...

Furthermore, Der p 2 has been shown to induce inflammatory allergenic effects via binding of Toll-like receptor 4 (TLR4) (12,13). Thus, Group 1 ...