Controlling NK Cell Responses

Controlling NK Cell Responses: Integration of Signals for Activation ...

This review will focus mainly on the regulation of NK cell responses through signals delivered by receptors that bind extracellular ligands.

Controlling natural killer cell responses: integration of signals for ...

Understanding how signals are integrated to control natural killer (NK) cell responsiveness in the absence of antigen-specific receptors has been a ...

Molecular checkpoints controlling natural killer cell activation and ...

Thus, NK cell effector function can be regarded as a surrogate marker of ongoing antitumor immune response, and its monitoring can be utilized ...

Natural Killer Cell Response - an overview | ScienceDirect Topics

Natural killer cell responses are controlled by inhibitory and stimulatory signals sent by diverse cell-surface receptors.

Natural killer cells in antiviral immunity | Nature Reviews Immunology

Natural killer (NK) cells play an important role in innate immune responses to viral infections. Here, we review recent insights into the role of NK cells in ...

Cell-intrinsic adrenergic signaling controls the adaptive NK cell ...

In summary, our findings suggest that cell-intrinsic adrenergic signaling promotes adaptive NK cell responses during viral infection and provide ...

Targeting Natural Killer Cells for Improved Immunity and Control of ...

Targeting Natural Killer Cells for Improved Immunity and Control of the Adaptive Immune Response · NK Cell Cells Are Innate Immune Killers · NK ...

Natural Killer Cell Response - an overview | ScienceDirect Topics

Natural killer (NK) cells are a key component of the innate immune response and play a major role in the control of tumors and microbial infections.

Nanoscale Colocalization of NK Cell Activating and Inhibitory ...

Natural killer (NK) cell activation is dependent on a different array of germline-encoded receptors capable of triggering effector responses against infection ( ...

Controlling natural killer cell responses: integration of signals for ...

Figure 1 Multiple signals control NK cell responses. An array of NK cell activation receptors bind to ligands on other cells. Target cell killing requires ...

Controlling Natural Killer Cell Responses: Integration of Signals for ...

... controlling NK cell responses and, paradoxically, in maintaining NK cells in a state of responsiveness to subsequent activation events, a process referred ...

Coordinated Viral Control by Cytotoxic Lymphocytes Ensures ...

However, although adaptive NK cell responses share similar clonal expansion kinetics with anti- gen-specific T cells, whether these adaptive ...

Inclusion criteria: how NK cells gain access to T cells - JCI

Work from several groups has shown that NK cells regulate T cell responses in the context of viral infections. For example, following an acute ...

Natural killer (NK) cell-derived extracellular-vesicle shuttled ... - eLife

NK cells also modulate immune responses, particularly T cell function. NK cells promote T cell differentiation, proliferation, and cytokine ...

Toll-like receptor 3 regulates NK cell responses to cytokines and ...

NK cell responses are controlled by the integration of signals from germline-encoded activating and inhibitory receptors that recognize molecules expressed ...

Natural Killer Cells | British Society for Immunology

NK cells are best known for killing virally infected cells, and detecting and controlling early signs of cancer.

Natural killer cell cytotoxicity and its regulation by inhibitory receptors

NK cells express many MHC-I-specific inhibitory receptors. Signals from MHC-I-specific inhibitory receptors tightly control NK cell cytotoxicity ...

Natural Killer Cells (NK Cells) Research Areas - R&D Systems

Natural killer cells (NK cells) are innate lymphoid cells that function as both cytotoxic effectors and regulators of immune responses.

Maintaining the Balance: Regulation of NK Cell Activity - MDPI

NK cells are crucial components of the innate immune response, playing a vital role in early responses to tumors, viral infections, and organ transplants [7].

Natural Killer Cells and Their Role in Immunity - EMJ

NK cells are a key component of the immune response and play vital roles in controlling and eliminating both virally-infected and cancer cells.