Controlling seizures in newborns with hemimegalencephaly

Children with hemimegalencephaly can develop horrible seizures within the first hours or days of life. According to published research, every ...

Treating newborns with hemimegalencephaly by inducing strokes

The seizures often result in severe cognitive delays and hemiparesis. The standard treatment is an anatomic hemispherectomy — surgical removal ...

Hemimegalencephaly: Causes, Symptoms & Treatment

Seizure treatment starts with anti-seizure medication. Some children with hemimegalencephaly may be able to control their seizures ...

Hemimegalencephaly - Child Neurology Foundation

Treatment for HME most often includes treating seizures. Seizure treatment starts with anti-seizure medication. However, seizures are often difficult to control ...

Seizure Outcome in an Infant after Hemispherectomy - PMC - NCBI

Isolated hemimegalencephaly (iHME) is a rare form of congenital malformation of cortical development characterized by enlargement of all or part of one ...

Hassani's Story: Hemispherotomy to Control Seizures from ...

Diagnosis of hemimegalencephaly · Hemispherotomy for lasting seizure control · Hemispherotomy for Hassani · Footer · Join the conversation. · Language Assistance/ ...

Definitive treatment of seizures due to hemimegalencephaly in ...

There is an unmet clinical need to control drug- resistant seizures in neonates and young infants with HME. This rare population of ...

Brain Inflammation in an Infant With Hemimegalencephaly ...

The immaturity and dysfunction of neurons have been suggested as the probable underlying cause of the intractable epilepsy. However, this does not fully explain ...

Hemimegalencephaly - Symptoms, Causes, Treatment | NORD

Anti-seizure medications typically are not effective in controlling seizures in HME and thus, surgery is often recommended to control the seizures. If the ...

Inducing strokes in newborns to treat hemimegalencephaly - YouTube

... seizures and improve neurodevelopmental outcomes in newborns under three months old with hemimegalencephaly (HME). The procedure, called an ...

Hemispherotomy in Infants with Hemimegalencephaly: Long-Term ...

We can reach good seizure control in infants with HME. Neuropsychological trajectories in HME patients may be characterized by moderate to ...

technical considerations for 'endovascular embolic hemispherectomy'

Conclusion Endovascular hemispherectomy can be safely used to provide definitive treatment of HME-related epilepsy in neonates and young infants when ...

Case Report Evolution of epilepsy in hemimegalencephaly from ...

Hemispherectomy has been performed in adulthood for similar indications, with good outcomes in terms of seizure control with 55–92% becoming seizure free [11], ...

Hemimegalencephaly - Why hemispherectomy is usually required

Functional outcomes are closely tied to seizure control and whether the brain malformation is present on both sides of the brain. It is ...

"Definitive treatment of seizures due to hemimegalencephaly in ...

Definitive treatment of seizures due to hemimegalencephaly in neonates and young infants by transarterial embolization: technical considerations ...

Hemimegalencephaly and intractable focal seizures related to ...

Hemimegalencephaly can produce intractable focal epilepsy and has been associated with various genetic causes, including NPRL3 mutations. We ...

Hemimegalencephaly - Pediatric Neurosurgery - UCLA Health

A surgery called a hemispherectomy is often required to control the seizures. In most cases, a functional hemispherectomy can be performed to fully disconnect ...

Seizure outcome in an infant after hemispherectomy

... hemimegalencephaly. Initial treatment with antiepileptic drugs (AEDs) was successful in controlling her seizures, but later on the seizures became ...

Long-term developmental outcome after early hemispherotomy for ...

Epileptic seizures occur in up to 93% of patients with HME, and seizure onset after 6 months of age is rare [2]. Hemimegalencephaly is one of the main causes of ...

Hemimegalencephaly and intractable seizures associated with the ...

Hemispherectomy is usually necessary to provide effective seizure control. The exact etiology of HME is not fully understood, but involves a ...