Coronavirus Infection Modulates the Unfolded Protein Response ...

The UPR is activated in response to a variety of ER stresses (calcium flux, unfolded proteins, and lipid depletion) and functions to upregulate the production ...

Coronavirus infection modulates the unfolded protein response and ...

During coronavirus replication, viral proteins induce the formation of endoplasmic reticulum (ER)-derived double-membrane vesicles for RNA synthesis, ...

ABSTRACTDuring coronavirus replication, viral proteins induce the formation of endoplasmic reticulum (ER)-derived double-membrane vesicles for RNA synthesis ...

The Role of Unfolded Protein Response in Coronavirus Infection ...

Activation of the three branches of UPR (PERK, IRE1, and ATF6) modulates various signaling pathways, such as innate immune response, microRNA, ...

The Role of Unfolded Protein Response in Coronavirus Infection ...

Activation of the three branches of UPR (PERK, IRE1, and ATF6) modulates various signaling pathways, such as innate immune response, microRNA, ...

Modulation of SARS-CoV-2 Spike-induced Unfolded Protein ...

evokes Unfolded Protein Response (UPR) and possibly autophagy, which could all attribute to the pathophysiology of the viral infections. To date ...

Insights into the Activation of Unfolded Protein Response ... - MDPI

... Unfolded Protein Response Mechanism during Coronavirus Infection ... Modulate Autophagy Induction in Cells Infected with Coronavirus Infectious Bronchitis Virus.

Coronavirus Infection Modulates the Unfolded Protein Response ...

Here, we report that infection by the murine coronavirus mouse hepatitis virus (MHV) triggers the proximal UPR transducers, as revealed by monitoring the IRE1- ...

SARS-CoV-2 activates ER stress and Unfolded protein response

Interestingly, the authors compared the A549 cells infected with SARS-CoV-2 and IAV and found UPR modulated only in SARS-CoV-2 infection.

Induction and modulation of the unfolded protein response during ...

Porcine deltacoronavirus (PDCoV) is an emerging enteropathogenic coronavirus that has the potential for cross-species infection. Many viruses have been reported ...

A pharmacological strategy against coronavirus infection - PLOS

Coronavirus infection induces the unfolded protein response (UPR), a cellular signalling pathway composed of three branches, triggered by unfolded proteins in ...

Coronavirus infection, ER stress, apoptosis and innate immunity

Activation of the three branches of UPR modulates a wide variety of signaling pathways, such as mitogen-activated protein (MAP) kinase activation, autophagy, ...

[PDF] Manipulation of the unfolded protein response: A ...

Coronavirus infection induces the unfolded protein response (UPR), a cellular signalling pathway composed of three branches, triggered by unfolded proteins ...

Live and let die: signaling AKTivation and UPRegulation dynamics ...

Here, we review the role of the AKT and UPR pathways and their interaction in relation to SARS-CoV-2 infection as well as in tumor onset and progression.

The Role of Unfolded Protein Response in Coronavirus Infection ...

Activation of the three branches of UPR (PERK, IRE1, and ATF6) modulates various signaling pathways, such as innate immune response, microRNA, autophagy, and ...

a pharmacological strategy against coronavirus infection - Abstract

Based on the strong UPR activation brought about by MHV infection, we hypothesised that pharmacological manipulation of this pathway could be used to modulate ...

Coronavirus-induced ER stress response and its involvement in ...

Several coronavirus proteins modulate coronavirus-induced UPR. •. During coronavirus infection, PERK is pro-apoptotic and IRE1 is anti-apoptotic. •.

Role of the early secretory pathway in SARS-CoV-2 infection

S.C.. Baker . 2008 . Coronavirus infection modulates the unfolded protein response and mediates sustained translational repression . J. Virol.

Human Coronavirus: Host-Pathogen Interaction | Annual Reviews

J, Chen Z, Brewer JW, Baker SC 2008. Coronavirus infection modulates the unfolded protein response and mediates sustained translational ...

Coronavirus Infection Modulates the Unfolded Protein Response ...

Coronavirus Infection Modulates the Unfolded Protein Response and Mediates Sustained Translational Repression. John Bechill, Zhongbin Chen, Joseph W. Brewer ...