Correlation of PSMA PET and Post|therapy SPECT Imaging Metrics ...

Correlation of PSMA PET and Post-therapy SPECT Imaging Metrics ...

The degree to which absorbed doses to organs-at-risk and tumor targets are associated with imaging metrics from the pre-therapy PET or post-therapy SPECT scans ...

Comparison of Post-Therapy 4 and 24-hour 177Lu-PSMA SPECT ...

Semi-quantitative TTV on 4-hour and 24-hour 177Lu-PSMA SPECT/CT both correlated strongly to baseline 68Ga PSMA-PET/CT with Pearson's coefficient ...

Same-day post-therapy imaging with a new generation whole-body ...

We successfully implemented same-day post-therapy SPECT/CT after [ 177 Lu]Lu-PSMA-617 infusions. Quantitation of 1-2 h post-therapy SPECT/CT ...

Impact of PSMA PET on Prostate Cancer Management - PMC

Following initial imaging, all patients crossed over to be staged with PSMA PET or conventional imaging. The median serum PSA levels in this ...

Quantitative imaging for 177Lu-PSMA treatment response ... - Frontiers

Post-177Lu-PSMA SPECT/CT offers the unique opportunity of assessment of response to treatment while the therapy is ongoing, without the need to administer a ...

SPECT Imaging Response with PSMA Radionuclide Therapy ...

And there was a very nice correlation between the volumes on the two. You definitely don't see smaller lesions on SPECT compared to PET. The ...

Diagnostic efficacy of [99mTc]Tc-PSMA SPECT/CT for prostate cancer

In particular, [99mTc]Tc-PSMA SPECT/CT showed a higher specificity and positive likelihood ratio than [68Ga]Ga-PSMA PET/CT, while its ...

A comparative analysis with 18 F-PSMA PET/CT. - ASCO Publications

The lowest diameter of positive LN detected by SPECT/CT was 4 mm (range 4-18). Pearson-correlation coefficient between PSA and TTV SPECT was r=0.68 (p=0.003) ...

Current status of PSMA-targeted imaging and therapy - Frontiers

In the region-based analysis, the sensitivity and specificity of 68Ga-PSMA-11 PET/CT were 97.7% and 100%, respectively, and those of 99mTc-DPD-SPECT were 69.4% ...

68Ga-PSMA PET/CT versus CT and bone scan for investigation of ...

This study provides evidence that PSMA PET/CT has a higher detection rate of lesions when compared with CTAP and BS in patients with biochemical recurrence post ...

PSMA PET imaging in the diagnosis and management of prostate ...

In a recent post hoc analysis involving 270 patients, PSMA PET imaging was found to alter patient management in 19% of cases [39]. As a result, ...

Is There a Role of Interim PSMA PET in Chemotherapy of Prostate ...

However, since the flare phenomenon is comparatively uncommon on PSMA PET compared to bone scans, a confirmatory scan is not required. Two new lesions should ...

68Ga-PSMA PET/CT in early relapsed prostate cancer patients after ...

Statistical analysis of 32 patients with positive imaging findings showed a significant correlation between PSMA PET/CT scan positivity and GS ( ...

PSMA Ligands for Radionuclide Imaging and Therapy of Prostate ...

Preclinical imaging using [18F]-DCFPyL demonstrated PSMA-expressing to PSMA-negative tumor ratios exceeding 300:1 at 2 h post-injection with minimal non-target ...

[68Ga]Ga-PSMA-11 PET imaging as a predictor for absorbed doses ...

While a large inter-patient variation in lesion kinetics was observed, PET/SPECT absorbed dose ratio was 1.3 ± 0.7 (range: 0.4–2.7, correlation ...

Nonprostatic diseases on PSMA PET imaging: a spectrum of benign ...

PSMA PET imaging was originally used to assess biochemical recurrence of prostate cancer (PCa), but its clinical use was promptly extended ...

Imaging and therapy in prostate cancer using ... - Oxford Academic

Prostate specific membrane antigen (PSMA) directed PET imaging has rapidly transformed prostate cancer workup over the past decade and paved the way for a ...

:: KJR :: Korean Journal of Radiology

Pre-Treatment [18F]Florastamin PSMA PET vs. Absorbed Dose ... The absorbed dose coefficient of the salivary glands showed a positive correlation ...

Keeping up with the prostate-specific membrane antigens (PSMAs ...

65% and specificity of 82% vs. 76%, especially in nodes not fulfilling the size criteria on CT. A similar study performed PSMA-11 PET/CT imaging in 30 patients ...

Investigation of image-based lesion and kidney dosimetry protocols ...

177Lu-PSMA therapy has been successfully used to prolong the survival of patients with metastatic castration-resistant prostate cancer.