Correlation of mRNA and protein levels

Relationship between differentially expressed mRNA and ... - Nature

Genome-wide correlation between expression levels of mRNA and protein are notoriously poor, hovering around 40% explanatory power across many ...

Unraveling the complex relationship between mRNA and protein ...

Based on this central dogma of molecular biology, it is widely accepted that protein levels are primarily determined by the abundance of their respective mRNAs.

The utility of protein and mRNA correlation - PMC

Their major conclusion succinctly stated that '[they] found that the correlation between mRNA and protein levels was insufficient to predict protein expression ...

Correlation of mRNA and protein levels: Cell type-specific gene ...

Expression levels of mRNA and protein by cell types exhibit a range of correlations for different genes. In this study, we compared levels ...

On the Dependency of Cellular Protein Levels on mRNA Abundance

This is particularly relevant when evaluating protein/mRNA correlation for a single gene (Figure 1A), as the transcript isoforms expressed may ...

Reassessing the relationship between mRNA levels and protein ...

A long-standing paradigm in molecular biology assumes a direct relationship between increases in mRNA levels and the abundance of the ...

Global variability analysis of mRNA and protein concentrations ...

Concentrations of mRNAs and proteins show considerable variability across tissues, and it is well known that mRNA and protein levels are poorly ...

Experimental reproducibility limits the correlation between mRNA ...

In general, the mRNA-protein correlation increases with protein reproducibility for samples from both healthy and diseased conditions and ...

Comparing protein abundance and mRNA expression levels on a ...

Additionally, as mRNA is eventually translated into protein, one might assume that there should be some sort of correlation between the level of ...

Simultaneous quantification of mRNA and protein in single cells ...

Less than 20% of these loci had concordant effects on mRNA and protein of the same gene. Most loci influenced protein but not mRNA of a given ...

Gene‐specific correlation of RNA and protein levels in human cells ...

A comparison of absolute protein copy numbers with mRNA levels across human tissues and cell lines shows that protein levels correlate well with ...

Correlation of mRNA and protein in complex biological samples

They found that varying mRNA levels correlated well with corresponding protein levels (r p = 0.89), whereas genes expressed at steady levels had ...

A gene's mRNA level does not usually predict its protein level

The average R2 or Rs correlation coefficient from 20 plots of mRNA versus protein concentration (from six kinds of mammalian cultured cells and ...

Discordant Protein and mRNA Expression in Lung Adenocarcinomas

Correlation coefficient values were not related to protein abundance. Further, no significant correlation between mRNA and protein expression was found (r = − ...

The relationship of mRNA with protein expression in CD8+ T cells ...

In summary, we show that the limited relation between the mRNA and protein levels is gene class. 379 specific and is defined by sequence conservation and by ...

Spatiotemporal analysis of mRNA-protein relationships enhances ...

This results in a moderate correlation between mRNA and protein levels in humans, mice, zebrafish, Drosophila,, C. elegans, and yeast. The ...

Correlations between mRNA and protein levels vary widely and are...

The protein is closer to the target of natural selection but gene expression is typically measured as the amount of mRNA. The broad assumption that mRNA levels ...

The relationship of mRNA with protein expression in CD8+ T cells ...

Yet, gene class stratification revealed a function-specific correlation of mRNA with protein expression. This gene class-specific expression pattern associated ...

How is mRNA expression predictive for protein ... - Semantic Scholar

The results showed an overall positive correlation between mRNA and protein expression levels, and the moderate and varied correlations suggest that mRNA ...

Correlation of mRNA and protein expression levels. The plot shows ...

Download scientific diagram | Correlation of mRNA and protein expression levels. The plot shows the correlation between mRNA abundance (parameter x ) and ...