Cost|effectiveness of polygenic risk profiling for primary open|angle ...

Cost-effectiveness of polygenic risk profiling for primary open-angle ...

Primary open-angle glaucoma (POAG) is the most common subtype of glaucoma. We evaluate the cost-effectiveness of polygenic risk score (PRS) ...

Cost-effectiveness of polygenic risk profiling for primary open-angle ...

We describe and model the cost-efficacy of incorporating a polygenic risk score for POAG screening in Australia and the UK for the first time and results ...

Cost-effectiveness of polygenic risk profiling for primary open-angle ...

We used a Markov cohort model to evaluate the cost-effectiveness of implementing polygenic risk profiling as a new POAG-screening approach in the UK and ...

Cost-effectiveness of polygenic risk profiling for primary open-angle ...

Costs, QALYs, and. Years of Blindness are discounted lifetime totals per person. ICERs are calculated by comparing the Genetic Screening to the ...

Cost-Effectiveness of Polygenic Risk Profiling for Primary Open ...

We describe and model the cost-efficacy of incorporating a polygenic risk score for POAG screening in Australia and the UK for the first time.

[PDF] Cost-effectiveness of polygenic risk profiling for primary open ...

The cost-efficacy of incorporating a polygenic risk score for POAG screening in Australia and the UK for the first time is described and results indicated ...

Cost-effectiveness of polygenic risk profiling for primary open-angle ...

Cost-effectiveness of polygenic risk profiling for primary open-angle glaucoma in the United Kingdom and Australia. Liu Q, Davis J, Han X, Mackey DA, ...

Cost-effectiveness of polygenic risk profiling for primary open-angle ...

We evaluate the cost-effectiveness of polygenic risk score (PRS) profiling as a screening tool for POAG. Methods: We used a Markov cohort model to evaluate the ...

[In Press] Cost-effectiveness of polygenic risk profiling for primary ...

BACKGROUND: Primary open-angle glaucoma (POAG) is the most common subtype of glaucoma. We evaluate the cost-effectiveness of polygenic risk score (PRS) ...

Cost-Effectiveness of Polygenic Risk Profiling for Primary Open ...

Background: Primary open-angle glaucoma (POAG) is the most common subtype of glaucoma. We evaluate the cost-effectiveness of polygenic risk score (PRS) ...

Genetic Risk Profiling May Be Cost-Effective for Identifying POAG

Incorporating polygenic risk scores into primary open-angle glaucoma (POAG) screening may be cost-effective and reduce economic burdens on ...

Cost-effectiveness of polygenic risk profiling for primary open-angle ...

Cost-effectiveness of polygenic risk profiling for primary open-angle glaucoma in the United Kingdom and Australia. Qinqin Liu, John Davis, Xikun Han, David ...

Cost-effectiveness of polygenic risk profiling for primary open-angle ...

Cost-effectiveness of polygenic risk profiling for primary open-angle glaucoma in the United Kingdom and Australia · List of references · Publications that cite ...

Evaluating the cost-effectiveness of polygenic risk score-stratified ...

Results of a sensitivity analysis based on multiply imputed data are shown in Supplementary Table 7. The results were similar to the primary ...

Polygenic Risk Score Improves Prediction of Primary Open Angle ...

POAG risk increased 1.36% with each higher PRS decile, with conversion ranging from 9.5% in the lowest PRS decile to 21.8% in the highest decile. Comparison of ...

Cost-Effectiveness of Polygenic Risk Scores to Guide Statin Therapy ...

The optimal economic strategy was when intermediate risk individuals with a PRS in the top 70% are eligible for statins while the lowest 1% are ...

Health economic analysis of polygenic risk score use in primary ...

We aimed to model the impact and cost effectiveness of incorporating a Polygenic risk scores (PRS) into the cardiovascular disease CVD primary prevention ...

Polygenic Risk Score Important to Track POAG Onset

Polygenic risk score was valuable in enhancing risk prediction models for primary open-angle glaucoma (POAG.

Polygenic Risk Scores Driving Clinical Change in Glaucoma

Cost-effectiveness of polygenic risk profiling for primary open-angle glaucoma in the United Kingdom and Australia. . Eye 37:(11):2335–43.

Diversity in Polygenic Risk of Primary Open-Angle Glaucoma - MDPI

Prioritizing diversity in the discovery of risk variants will improve the performance and utility of GRS and PRS-derived risk estimation for ...