Critical Role for TNF in the Induction of Human Antigen|Specific ...

Critical role for TNF in the induction of human antigen ... - PubMed

TNF is a pleiotropic cytokine with differential effects on immune cells and diseases. Anti-TNF therapy was shown to be effective in ...

Critical Role for TNF in the Induction of Human Antigen-Specific ...

Abstract. TNF is a pleiotropic cytokine with differential effects on immune cells and diseases. Anti-TNF therapy was shown to be effective in rheumatoid ...

Critical Role for TNF in the Induction of Human Antigen-Specific ...

We studied the role of TNF in the induction of Ag-specific regulatory T cells (Tregs) by tolerogenic vitamin D3-modulated human dendritic cells (VD3-DCs), which.

[PDF] Critical Role for TNF in the Induction of Human Antigen ...

Data point to a specific role for mTNF on VD3-DCs in the induction of Ag-specific regulatory T cells (Tregs) by tolerogenic vitamin D3-modulated human ...

Critical role for TNF in the induction of human antigen-specific ...

TNF is a pleiotropic cytokine with differential effects on immune cells and diseases. Anti-TNF therapy was shown to be effective in rheumatoid arthritis but ...

Critical Role for TNF in the Induction of Human Antigen-Specific ...

Abstract TNF is a pleiotropic cytokine with differential effects on immune cells and diseases. Anti-TNF therapy was shown to be effective in rheumatoid ...

Critical role for TNF in the induction of human antigen-specific ...

Critical role for TNF in the induction of human antigen-specific regulatory T cells by tolerogenic dendritic cells. by Fleur S Kleijwegt, Sandra Laban, ...

Critical Role for TNF in the Induction of Human Antigen ... - Altmetric

Critical Role for TNF in the Induction of Human Antigen-Specific Regulatory T Cells by Tolerogenic Dendritic Cells · The Journal of Immunology, August 2010.

TNF Blockade Maintains an IL-10 + Phenotype in Human Effector ...

Keywords: tumor necrosis factor, anti-TNF, TNF ... Critical role for TNF in the induction of human antigen-specific regulatory T cells by ...

Critical Role for Tumor Necrosis Factor–related Apoptosis-inducing ...

Our present results suggested that IFN-γ may regulate TRAIL-mediated tumor surveillance not only by regulating TRAIL expression on effector cells, but also by ...

Death by TNF: a road to inflammation | Nature Reviews Immunology

Hence, the necrotizing factor was named 'tumour necrosis factor' or 'TNF'. In the years after, the genes encoding the human and mouse TNF and ...

Critical Role of Tumor Necrosis Factor-α and NF-κB in Interferon-γ ...

The inclusion of anti-TNF-α-neutralizing antibody significantly inhibits IFN-γ-induced CD40 mRNA and CD40 promoter activity. IFN-γ-induced CD40 protein ...

The Key Role of TNF-TNFR2 Interactions in the Modulation of ...

In allergic rhinitis, TNF is essential for the recruitment of eosinophils to the site of allergic inflammation through the induction of adhesion ...

A critical role for suppression of a synergy between IL-2 and TNF-α

In contrast, CSA, which inhibited proliferation in MLR induced by B-cell lines, also inhibited TNF-α, IL-2 and IFN-γ synthesis. Together these data suggest that ...

Role of TNF–TNF Receptor 2 Signal in Regulatory T Cells and Its ...

TNFα plays a critical role in upregulation or downregulation of Treg activity. Deficiency in TNFR2 signaling is significant in various ...

A Critical Role of the p75 Tumor Necrosis Factor Receptor (p75TNF ...

... tumor necrosis factor receptor (p75TNF-R) accompanies development of specific human infla. ... Both TNF receptors are required for TNF-mediated induction of ...

TNF-α is critical for antitumor but not antiviral T cell immunity in mice

Therefore, in contrast to its limited role in in vivo proliferative responses to viral antigens, TNF-α is critical in promoting T cell proliferation to cross- ...

Contrasting effects of TNF and anti‐TNF on the activation of effector ...

TNFR2 is associated with greater suppressive functions when expressed by Treg cells, but is also associated with greater resistance to ...

The Role of Tumor Necrosis Factor Alpha (TNF-α) in Autoimmune ...

Physiologically, TNF-α is a crucial component for a normal immune response. TNF-α can activate the immune system to regulate; however, the ...

Tumor necrosis factor - Wikipedia

Excessive production of TNF plays a critical role in several inflammatory diseases, and TNF-blocking drugs are often employed to treat these diseases. TNF ...