Cumulative cisplatin dose in concurrent chemoradiotherapy for head ...

Results support the conclusion that the cumulative dose of cisplatin in concurrent chemoradiation protocols for HNSCC has a significant positive correlation ...

Optimal cumulative dose of cisplatin for concurrent ...

Several phase III clinical studies utilized high-dose cisplatin, either 100 mg/m2 every 3 weeks for three cycles [cumulative dose (CD), 300 mg/m2] or 40 mg/m2 ...

The Cumulative Cisplatin Dose Affects the Long-Term Survival ...

However, a cumulative dose of 200 mg/m2 cisplatin had been reported to be sufficient to yield a beneficial anti-tumor effect in other head and ...

Cumulative cisplatin dose in concurrent chemoradiotherapy for head ...

At the moment, the recommended cumulative dose of cisplatin that should be administered during radiotherapy seems to be at least 200 mg/m2, but ...

Optimal cumulative cisplatin dose for radio-sensitization in locally ...

Conclusions: This study confirms that a cumulative cisplatin dose of ~ 210 mg/m2 is optimum for increasing PFS in patients with head and neck ...

Concurrent chemoradiotherapy with cisplatin given once-a-week ...

High-dose cisplatin (100 mg/m2) delivered every three-weekly for 3 cycles during radiotherapy is considered contemporary standard of care in head neck cancers.

Cumulative cisplatin dose in concurrent chemoradiotherapy for head ...

"Cumulative cisplatin dose in concurrent chemoradiotherapy for head and neck cancer: A systematic review." Head & Neck 38(S1): E2151-E2158.

3-weekly or weekly cisplatin concurrently with radiotherapy for ...

Significantly more patients receive a cumulative cisplatin dose of ≥200 mg/m 2 , when treated with a 3-weekly schedule compared to weekly dosing.

Standard versus fractionated high-dose cisplatin plus radiation for ...

Chemoradiotherapy with high-dose cisplatin (HD-Cis: 100 mg/m2 q3w for three cycles) is the standard of care (SOC) in locally advanced head and neck squamous ...

Cumulative cisplatin dose in concurrent chemoradiotherapy for head ...

The optimal cumulative dose and timing of cisplatin administration in various concurrent chemoradiotherapy protocols for nonmetastatic head and neck ...

Optimal regimen of cisplatin in squamous cell carcinoma of head ...

A 2.2% OS benefit between the chemoradiotherapy group and the radiotherapy alone group was observed for every 10 mg increase in the cumulative cisplatin dose ( ...

Cisplatin Every 3 Weeks Versus Weekly With Definitive Concurrent ...

Concurrent chemoradiotherapy is an established component of the nonoperative management of locally advanced head and neck squamous cell ...

Standard versus fractionated high-dose cisplatin plus radiation for ...

Cumulative cisplatin dose in concurrent chemoradiotherapy for head and neck cancer: A systematic review. Head Neck 2016;38:E2151–8. https ...

Optimizing the cumulative cisplatin dose during radiotherapy in ...

A cumulative cisplatin dose of 240 mg/m2 is optimal in nasopharyngeal carcinoma. · Benefit of concurrent chemotherapy was mostly derived from locoregional ...

The impact of the cumulative dose of cisplatin during concurrent ...

Concurrent cisplatin chemotherapy was delivered to all of the patients. Chemotherapy was initiated on the same day as IMRT, and the cisplatin ...

Once-a-Week Versus Once-Every-3-Weeks Cisplatin ...

In locally advanced head and neck squamous cell carcinoma (LAHNSCC), high-dose (100 mg/m2) once-every-3-weeks cisplatin added to curative ...

A New Prognostic Instrument for Predicting the Probability of ... - MDPI

Many head and neck cancer patients assigned to definitive or adjuvant chemoradiation treatment do not complete the concurrent cisplatin dose.

Cumulative cisplatin dose in concurrent chemoradiotherapy for head ...

027) between cumulative cisplatin dose, independent of the schedule, and overall survival benefit was observed for higher doses. Conclusion ...

Low-Dose vs. High-Dose Cisplatin: Lessons Learned From 59 ...

Both groups received the same mean doses of chemotherapy and radiotherapy, but significantly more patients could tolerate cumulative doses of at least 200 mg/m2 ...

Long-Term Update of a Phase 3 Randomized Study Comparing ...

Cumulative cisplatin dose in concurrent chemoradiotherapy for head and neck cancer: a systematic review. Head Neck. 2016; 38:E2151-E2158.