Current status of the diagnosis and treatment of hemophagocytic ...

Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of defective apoptosis, a disruption of the regulatory pathway that terminates immune ...

Genetic alterations causing HLH, such as abnormalities of genes related to the inactivation of immune cells, have been discovered in adults. For the diagnosis ...

Hemophagocytic lymphohistiocytosis: current treatment advances ...

Hemophagocytic lymphohistiocytosis (HLH) is a rapidly progressing, life-threatening syndrome characterized by excessive immune activation, ...

Current status of the diagnosis and treatment of hemophagocytic ...

It is highly recommended that allogenic hematopoietic stem cell transplantation should be used in patients who become reactivated or are refractory to the ...

Treatment and prognosis of hemophagocytic lymphohistiocytosis

Literature review current through: Oct 2024. ... (See "Clinical features and diagnosis of hemophagocytic lymphohistiocytosis".) ... Often, the ...

Hemophagocytic Lymphohistiocytosis (HLH) | Symptoms, Diagnosis ...

Prompt treatment is very important for patients with HLH, as the condition is often fatal. The first treatments are typically used to stop the inflammation in ...

Hemophagocytic Lymphohistiocystosis | Johns Hopkins Medicine

In adults, many different conditions, including infections and cancer, can cause HLH. ... Your healthcare provider bases a diagnosis of HLH ... Treatment of HLH ...

Hemophagocytic Lymphohistiocytosis: Symptoms, Causes & Outlook

The condition is either acquired or genetic and there's no way to prevent it. Treatment is available and most effective with an early diagnosis.

Hemophagocytic Lymphohistiocytosis (HLH)

Without prompt diagnosis and treatment, HLH can lead to severe organ damage and death. ... condition – similar to treatment for primary HLH. ... current treatments.

Epidemiology, characteristics, and outcomes of adult ... - The Lancet

HLH is a rare and life-threatening disease, often requiring prompt diagnosis and treatment. In recent years, there has been a growing interest ...

Haemophagocytic syndromes: the importance of early diagnosis ...

Without proper treatment, HLH can be fatal. The risk of a rapid progression to multi-organ failure and central nervous system involvement leading to long-term ...

Recommendations for the management of hemophagocytic ...

Most information on the diagnosis and treatment of HLH comes from the pediatric literature. Although helpful in some adult cases, this raises ...

Hemophagocytic Lymphohistiocytosis - Symptoms, Causes, Treatment

Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening condition caused by an overactive, abnormal response of the immune system.

Clinical features and diagnosis of hemophagocytic lymphohistiocytosis

Literature review current ... (See "Treatment and prognosis of hemophagocytic ... Group Practice. Disclaimer: This generalized information is a ...

Recent advances in the diagnosis and treatment of hemophagocytic ...

Hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening disease of severe hyperinflammation caused by uncontrolled proliferation ...

438: case of rapid presentation, diagnosis, and treatment of ...

Introduction: Hemophagocytic lymphohistiocytosis (HLH) requiring ICU have been quoted as having greater than 50% mortality regardless of etiology and ...

How I treat hemophagocytic lymphohistiocytosis in the adult patient

Early diagnosis is essential because without treatment HLH is frequently fatal. In 2004, The Histiocyte Society proposed an updated set of criteria to aid in ...

Hemophagocytic lymphohistiocytosis in adults: Diagnosis and ...

Inherited forms produce symptoms in early childhood and are fatal in the absence of specific treatment. In adults, the clinical spectrum ranges from mild and ...

Lymphohistiocytosis (Hemophagocytic Lymphohistiocytosis)

Fever, hepatosplenomegaly, pancytopenia, lymphadenopathy, and rash often comprise the initial presentation. Rapid diagnosis and early treatment ...

Case report: Hemophagocytic lymphohistiocytosis complicated by ...

Early diagnosis of HLH can allow patients to receive appropriate treatment, such as HLH-94 protocol (i.e., etoposide and dexamethasone), with ...