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Cyanide Toxicity and Cyanokit


CYANOKIT® (hydroxocobalamin) | Cyanide Poisoning Treatment

INDICATION. CYANOKIT is indicated for the treatment of known or suspected cyanide poisoning. ... CYANOKIT is a registered trademark of SERB Sàrl, licensed by BTG ...

Treat Cyanide Poisoning With CYANOKIT® (hydroxocobalamin)

CYANOKIT for intravenous infusion is indicated for the treatment of known or suspected cyanide poisoning. If clinical suspicion of cyanide poisoning is high, ...

Say no to cyanokit. Pause at the 10, 10 threshold - PMC

As of 2016, Cyanokit (hydroxocobalamin) is available in the US and the European Union for treatment of cyanide poisoning, and its use has become widespread in ...

About Cyanide Poisoning | CYANOKIT® (hydroxocobalamin)

Cyanide poisoning may result from inhalation, ingestion, or dermal exposure to various cyanide-containing compounds, including smoke from closed-space fires.

Hydroxocobalamin - Medical Countermeasures Database - CHEMM

The action of Cyanokit in the treatment of cyanide poisoning is based on its ability to bind cyanide ions. Each hydroxocobalamin molecule can bind one cyanide ...

Cyanokit Label - accessdata.fda.gov

Cyanokit is indicated for the treatment of known or suspected cyanide poisoning. 1.2. Identifying Patients with Cyanide Poisoning. Cyanide poisoning may result ...

Cyanide, Housefires, and When to Give Hydroxocobalamin

It can cause an increase in blood pressure (which can be desirable in cyanide poisoning) and will result in red discoloration of the skin and ...

Cyanide Toxicity Treatment & Management - Medscape Reference

Available antidotes are hydroxocobalamin (Cyanokit) and sodium thiosulfate/sodium nitrite (Nithiodote). Both are given intravenously.

CYANOKIT® (hydroxocobalamin for injection) for intravenous infusion

If clinical suspicion of cyanide poisoning is high, administer CYANOKIT without delay. • Comprehensive treatment of acute cyanide intoxication requires support ...

Cyanide Antidote Kit - CHEMM

The starting dose of Cyanokit for adults is 5 g, (two 2.5 g vials) administered by IV infusion over 15 minutes. · Depending upon the severity of the poisoning ...

Cyanokit | European Medicines Agency (EMA)

Cyanokit is used as an antidote to treat known or suspected poisoning with cyanide, a highly poisonous chemical.

Does This Smoke Inhalation Victim Require Treatment with Cyanide ...

What Is the Pathophysiology of Cyanide Toxicity? · Hydrogen cyanide gas is a cellular asphyxiant which quickly dissociates into both hydrogen and cyanide ions ...

Cyanokit: Uses, Dosage, Side Effects, Warnings - Drugs.com

Cyanokit contains hydroxocobalamin, a form of vitamin B-12. It is used as an antidote to cyanide poisoning.

Apri 23, 2007: What is the CYANOKIT (hydroxocobalamin) antidote?

Cyanokit was FDA approved about a month ago. · Inhalation, ingestion or dermal exposure to cyanide-containing compounds may cause cyanide poisoning.

Evaluation of hydroxocobalamin use for the treatment of suspected ...

Hydroxocobalamin is used for cyanide toxicity after smoke inhalation, but diagnosis is challenging. Retrospective studies have associated hydroxocobalamin with ...

Frequently Asked Questions | CYANOKIT® (hydroxocobalamin)

CYANOKIT contains hydroxocobalamin, an antidote indicated for the treatment of known or suspected cyanide poisoning.

Cyanide Antidotes | OSHA.gov | Occupational Safety and Health ...

Due to the acute and lethal hazards presented by cyanide poisoning, an employer covered under OSHA's standard, Medical Services and First Aid, ...

Cost impact of hydroxocobalamin in the treatment of patients with ...

Use of hydroxocobalamin in patients with known or suspected cyanide poisoning from closed-space fire smoke inhalation may decrease hospital costs.

Cyanokit (hydroxocobalamin): Cyanide Antidote Dosage

Cyanokit (hydroxocobalamin injection) is the antidote to cyanide poisoning. Side effects, drug interactions, warnings, dosing, and pregnancy and ...

Cyanide Antidote Resources | CYANOKIT® (hydroxocobalamin)

In conjunction with CYANOKIT, treatment of cyanide poisoning must include immediate attention to airway patency, adequacy of oxygenation and hydration, ...


Hydroxocobalamin

Drug https://encrypted-tbn1.gstatic.com/images?q=tbn:ANd9GcSDIQDddxseYX4CMhUK1-dteDPr4EinnYikEApBnc8TV8TuTzzI

Hydroxocobalamin, also known as vitamin B₁₂ₐ and hydroxycobalamin, is a vitamin found in food and used as a dietary supplement. As a supplement it is used to treat vitamin B12 deficiency including pernicious anemia. Other uses include treatment for cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. It is given by injection into a muscle or vein, by pill or sublingually. Side effects are generally few.

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