DNA|binding Protein
DNA-binding protein - Wikipedia
DNA-binding proteins are proteins that have DNA-binding domains and thus have a specific or general affinity for single- or double-stranded DNA. ... Sequence- ...
The structure, function and evolution of proteins that bind DNA and ...
Key Points · DNA- and RNA-binding proteins (DRBPs) constitute a significant fraction of cellular proteins and have important roles in cells.
DNA Binding - an overview | ScienceDirect Topics
This facilitates structural studies of the isolated DNA-binding domains or their complexes with DNA using techniques that require low molecular weight proteins, ...
DNA-Binding Motifs in Gene Regulatory Proteins - NCBI
Gene regulatory proteins recognize short stretches of double-helical DNA of defined sequence and thereby determine which of the thousands of genes in a cell ...
DNA Binding - an overview | ScienceDirect Topics
DNA-binding domain: a folded protein domain that matches and binds to a region of DNA, allowing protein–DNA interactions.
DNA-Binding Proteins: Overview & Application - Excedr
DNA-binding proteins are proteins having an affinity for different DNA molecules. They contain DNA-binding sites to recognize and bind specific ...
Methods for Detecting Protein-DNA Interactions - US
The ChIP assay method allows analysis of DNA–protein interactions in living cells by treating the cells with formaldehyde or other crosslinking reagents in ...
Protein–DNA binding: complexities and multi-protein codes
We review the complexities in protein–DNA binding found at multiple levels and discuss how they confound the idea of simple recognition codes.
The structure, function and evolution of proteins that bind DNA and ...
Proteins that bind both DNA and RNA epitomize the ability to perform multiple functions by a single gene product. Such DNA- and RNA-binding proteins (DRBPs) ...
Binding protein ... A binding protein is any protein that acts as an agent to bind two or more molecules together. ... Most actin binding proteins bind on the actin ...
Geometric deep learning of protein–DNA binding specificity - Nature
We present Deep Predictor of Binding Specificity (DeepPBS), a geometric deep-learning model designed to predict binding specificity from protein–DNA structure.
An overview of the structures of protein-DNA complexes
This review provides a general overview of the DNA-binding structures that have been found, along with detailed descriptions of the individual protein families.
Protein–DNA/RNA Interactions: An Overview of Investigation ...
The present review proposes an overview of the approaches most commonly employed in proteomics applications for the identification of nucleic acid-binding ...
DNA–protein interaction studies: a historical and comparative analysis
This review intends to provide a historical context and compile the methods that describe DNA–protein interactions according to the purpose of each approach.
This subsection of the Function section specifies the position and type of each DNA-binding domain present within the protein.
Protein:DNA Interactions - Promega Corporation
Chromatin immunoprecipitation (ChIP) is a method used to determine whether DNA-binding proteins, such as transcription factors, associate with a specific ...
4KPY: DNA binding protein and DNA complex structure - RCSB PDB
DNA binding protein and DNA complex structure.
Protein−DNA binding in the absence of specific base-pair recognition
We identify a new protein−DNA binding mechanism induced by DNA sequence symmetry in the absence of specific base-pair recognition.
Purification or Removal of DNA-Binding Proteins - Sigma-Aldrich
Remove ionically bound proteins by washing with 0.5 CV of 2 M NaCl for 10 to 15 min. Remove precipitated or denatured proteins by washing with 4 CV of 100 mM ...
Protein-DNA binding: data, tools & models
JASPAR is an open-access database of curated, non-redundant transcription factor (TF) binding profiles stored as position frequency matrices ( ...