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DNA interactions


DNA interactions: understanding what your DNA is up to

DNA doesn't work alone, interacting with other nucleic acids – DNA and RNA – as well as different types of proteins. These interactions influence various ...

DNA–DNA interactions | The Aksimentiev Group

We combine fluorescence resonance energy transfer (FRET) measurements, precipitation assays, and molecular dynamics simulations to characterize the effect of ...

DNA–protein interaction studies: a historical and comparative analysis

This review intends to provide a historical context and compile the methods that describe DNA–protein interactions according to the purpose of each approach.

Methods for Detecting Protein-DNA Interactions - US

The ChIP assay method allows analysis of DNA–protein interactions in living cells by treating the cells with formaldehyde or other crosslinking reagents in ...

Protein–DNA/RNA Interactions: An Overview of Investigation ... - NCBI

The present review proposes an overview of the approaches most commonly employed in proteomics applications for the identification of nucleic acid-binding ...

Analysis of protein-DNA interactions in chromatin by UV induced ...

We present a workflow that allows mass spectrometric (MS) identification of proteins in direct contact with DNA in reconstituted and native chromatin after ...

Protein DNA Interaction - an overview | ScienceDirect Topics

The scientist should compare luciferase expression between conditions in which (1) no protein is present, (2) protein is present, and (3) the regulatory ...

DNA-binding protein - Wikipedia

DNA-binding proteins are proteins that have DNA-binding domains and thus have a specific or general affinity for single- or double-stranded DNA. ... Sequence- ...

DNA Interactions with Proteins - News-Medical

During the process of complex formation, hydrogen bonds between the polar amino acids and the atoms of the DNA molecule augment the affinity of ...

Interactions with DNA - an overview | ScienceDirect Topics

The interplay between protein and DNA are ubiquitous in nature and governs several cellular processes (replication, transcription, translation, chromosomal ...

Energetics of protein-DNA interactions - PubMed

Protein-DNA interactions are vital for many processes in living cells, especially transcriptional regulation and DNA modification.

Protein:DNA Interactions - Promega Corporation

Chromatin immunoprecipitation (ChIP) is a method used to determine whether DNA-binding proteins, such as transcription factors, associate with a specific ...

Determining the specificity of protein–DNA interactions - Nature

Traditional methods for determining the specificity of DNA-binding proteins are slow and laborious, but several new high-throughput methods can provide ...

Introduction to Protein-DNA Interactions: Structure, Thermodynamics ...

Describes what we know about protein–DNA interactions from the complementary perspectives of molecular and structural biology and bioinformatics.

Understanding DNA interactions in crowded environments with a ...

We use a coarse-grained model of DNA to study the kinetics and thermodynamics of DNA duplex and hairpin formation in crowded environments.

Protein–DNA/RNA Interactions: An Overview of Investigation ...

The present review proposes an overview of the approaches most commonly employed in proteomics applications for the identification of nucleic acid-binding ...

Amino acid–base interactions: a three-dimensional analysis of ...

We investigate hydrogen bonds, van der Waals contacts and water-mediated bonds in 129 protein–DNA complex structures.

Genome-Wide Mapping of in Vivo Protein-DNA Interactions - Science

To map these protein-DNA interactions comprehensively across entire mammalian genomes, we developed a large-scale chromatin immunoprecipitation ...

DNA-Binding Proteins: Overview & Application - Excedr

DNA-binding proteins are proteins having an affinity for different DNA molecules. They contain DNA-binding sites to recognize and bind specific ...

Comprehensive Genome-wide Protein-DNA Interactions Detected at ...

We show an unprecedented view into genome-wide binding of the yeast transcription factors Reb1, Gal4, Phd1, Rap1, and human CTCF.