Events2Join

De|Escalation from High| or Moderate|Efficacy ...


De-Escalation from High- or Moderate-Efficacy ... - Practical Neurology

De-escalating from a high- or moderate-efficacy disease modifying therapy (DMT) to a low-efficacy DMT for treating MS is associated with similar safety and ...

Escalating to medium‐ versus high‐efficacy disease modifying ...

Escalating to medium‐ versus high‐efficacy disease modifying therapy after low‐efficacy treatment in relapsing remitting multiple sclerosis.

Escalation Versus Induction/High-Efficacy Treatment Strategies for ...

After more than 2 decades of recommending an escalating strategy for the treatment of most patients with multiple sclerosis, ...

Escalating to medium‐ versus high‐efficacy disease modifying ...

Escalating to medium- versus high-efficacy disease modifying therapy after low-efficacy treatment in relapsing remitting multiple sclerosis.

How do you decide between escalation to a high efficacy DMT

How do you decide between escalation to a high efficacy DMT versus switching to a different moderate efficacy DMT in patients with poorly controlled multiple ...

Bridging the Gap, De-Escalation of MS Disease Modifying Therapies

In a recent study of 135 patients with MS, investigators analyzed the safety of de-escalation of DMT from high or moderate efficacy to low-efficacy treatment.

MS treatment de-escalation: review and commentary

Treatment de-escalation can involve various strategies, such as extended or reduced dosing, switching from high-efficacy DMTs having higher ...

Escalation or high-efficacy disease-modifying therapies in multiple ...

Escalating treatment means starting with the safest disease-modifying therapies with moderate effect. High-efficacy therapies mean starting with a strong ...

Does initial high efficacy therapy in multiple sclerosis surpass ...

Highlights · Direct initiation of moderate-high efficacy therapy seems beneficial. · Moderate-high efficacy therapy does not lead to treatment switch due to ...

Evaluating the Effect of Disease Duration in High Efficacy Versus ...

Evaluating the Effect of Disease Duration in High Efficacy Versus Mid Efficacy Disease Modifying Therapies: Could This Help in Deciding When to De-escalate?

Treatment Escalation vs Immediate Initiation of Highly Effective ...

Escalation of treatment efficacy ... Timing of high-efficacy therapy for multiple sclerosis: a retrospective observational cohort study.

Escalation or high-efficacy disease-modifying therapies in multiple ...

Disease-modifying therapies for MS are divided into escalation therapies and high-efficacy therapies. Escalating treatment means starting with ...

Dr Patricia Coyle on Escalation vs High-Efficacy Induction in MS

Induction is a subset of high-efficacy agents that are given for a short period of time and have a long-lasting effect. So I think the first ...

Retrospectively Exploring De-Escalation of Multiple Sclerosis ...

One area of interest is de-escalation, which involves transitioning patients from high or moderate efficacy disease-modifying therapies (DMTs) ...

An Argument for De-escalation as a Treatment Paradigm for Patients ...

... high efficacy, de- escalation, escalation. Page 2. Vollmer et al. DMT De-escalation in MS. INTRODUCTION. Multiple sclerosis (MS) is an ...

An argument for broad use of high efficacy treatments in early ...

Two potential treatment frameworks have been articulated. Some advocate an escalation approach, positing that a premium should be placed on ...

Escalation vs. Early Intense Therapy in Multiple Sclerosis - MDPI

The “escalation strategy” consists of starting treatment with drugs of low side-effect profile and low efficacy, and “escalating” to drugs of higher efficacy— ...

Timing of high-efficacy therapy in relapsing-remitting multiple sclerosis

However, the most common treatment strategy is to commence first-line therapies, followed by treatment escalation in patients who continue to experience on- ...

Effectiveness and Safety of Early High-Efficacy Versus... - LWW

Escalation refers to starting treatment in newly diagnosed patients with less efficacious but relatively safe agents and eventually moving on to more ...

(PDF) Evolution of Disease Modifying Therapy Benefits and Risks

Background Strategies for sequencing disease modifying therapies (DMTs) in multiple sclerosis (MS) patients include escalation, high ...