Defining the Genes Required for Survival of Mycobacterium bovis in ...

In this study, we utilize transposon insertion sequencing in M. bovis AF2122/97 to determine the genes required for survival in cattle.

Defining the genes required for survival of Mycobacterium bovis in ...

The highest levels of attenuation seen were in genes involved in the synthesis of the cell wall virulence lipids PDIMs (ppsABCDE and mas with ...

Defining the genes required for survival of Mycobacterium bovis in ...

essentiality in Mycobacterium tuberculosis. Gene 765. 507. 13. Sassetti CM, Rubin EJ. 2003. Genetic requirements for mycobacterial survival ...

Defining the Genes Required for Survival of Mycobacterium bovis in ...

This is the first report of the genetic requirements of an animal-adapted member of the Mycobacterium tuberculosis complex (MTBC) in a ...

Defining the genes required for survival of Mycobacterium bovis in ...

bovis to determine the genes required for survival in cattle. We identify genes encoding established mycobacterial virulence functions such as ...

Genes required for survival and proliferation of Mycoplasma bovis in ...

Thirteen genes previously classified as dispensable for the axenic growth of M. bovis were found to be essential for the growth of M. bovis in ...

Genetic requirements for mycobacterial survival during infection

A total of 194 genes that are specifically required for mycobacterial growth in vivo were identified. The behavior of these mutants provides a detailed view of ...

Transposon libraries identify novel Mycobacterium bovis BCG genes ...

Although our data highlights the in vivo requirement for many previous recognised virulence factors, the majority of the genes identified as ...

Mycobacterium bovis and its impact on human and animal ...

Defining the genes required for survival of Mycobacterium bovis in the bovine host offers novel insights into the genetic basis of survival ...

Comprehensive identification of conditionally essential genes in ...

By using TraSH, we have defined the set of genes required for growth of Mycobacterium bovis bacillus Calmette–Guérin on minimal but not rich medium. Genes of ...

Inactivation of the Mycobacterium bovis homologue of the ...

One approach to discover possible virulence genes is to use comparative genomics to identify regions of difference (RD) across the genomes. This approach is ...

Defining the genes required for survival of Mycobacterium bovis in ...

Supplementary dataset from "Defining the genes required for survival of Mycobacterium bovis in the bovine host offers novel insights into ...

The complete genome sequence of Mycobacterium bovis

The genome sequence offers major insight on the evolution, host preference, and pathobiology of M. bovis, implying that differential gene expression may be ...

Genes required for mycobacterial growth defined by high density ...

Mycobacterium leprae is a close relative of M. tuberculosis, with few unique genes of its own. Mycobacterium leprae grows remarkably slowly in ...

Defining the genes required for survival of Mycobacterium bovis in ...

Defining the genes required for survival of Mycobacterium bovis in the bovine host offers novel insights into the genetic basis of survival of pathogenic ...

The Genetic Requirements for Fast and Slow Growth in Mycobacteria

We identified 84 genes that are exclusively required for slow growth (69 hours doubling time) and 256 genes required for switching from slow to fast growth.

Complete Genome Sequencing of Mycobacterium bovis SP38 and ...

Mycobacterium bovis causes bovine tuberculosis and is the main organism responsible for zoonotic tuberculosis in humans. We performed the ...

Expression of non-replicating persistence associated genes of ...

DosR genes were first described as important for long-term survival of M. tuberculosis and M. bovis Bacillus Calmette-Guérin (BCG) hypoxic and NO-exposed ...

Mycobacterium bovis: From Genotyping to Genome Sequencing

The type strain was defined as M. bovis ATCC 19210, still referenced in the most recent Bergey's Manual of Systematic Bacteriology [64], along with CIP 105234 ...

The microbiology of M. bovis - Bovine TB | TB Hub

If M. bovis is isolated and identified in the laboratory, it can be further typed using a genetic typing method called whole genome sequencing (WGS) so that ...