Dengue Virus Pathogenesis

Current Understanding of the Pathogenesis of Dengue Virus Infection

The pathogenesis of dengue virus infection is attributed to complex interplay between virus, host genes and host immune response.

Dengue Virus Pathogenesis: an Integrated View - PubMed Central

The pathogenesis of DHF and DSS involves viral virulence factors and detrimental host responses, collectively resulting in abnormal hemostasis and increased ...

Dengue virus pathogenesis and host molecular machineries

This review aims to summarize the complex interaction between DENV and the host cellular machinery, comprising regulatory mechanisms at various molecular ...

Dengue virus infection: Pathogenesis - UpToDate

Blood and bone marrow — Leukopenia, thrombocytopenia, and a hemorrhagic diathesis are the typical hematologic findings in DENV infections.

CDC-DCCM-Pathogenesis of Severe Dengue

The most widely-cited hypothesis for the pathogenesis of severe dengue is antibody-dependent enhancement (ADE).

Dengue: Practice Essentials, Background, Pathophysiology

Dengue fever is a mosquito-borne viral disease caused by 1 of 4 closely related but antigenically distinct serotypes of dengue virus, serotypes DENV-1 through ...

Dengue virus infection – a review of pathogenesis, vaccines ...

In this review, the recent development of neutralizing antibodies, antiviral agents, and vaccine candidates in therapeutic platform for DENV infection will be ...

Production, Transmission, Pathogenesis, and Control of Dengue ...

Dengue virus infection usually spreads through bites of infected female mosquitos of genus Aedes, especially by the Aedes aegypti and Ae.

Epidemiology, biology, pathogenesis, clinical manifestations, and ...

It is caused by being bitten by a dengue virus-infected female mosquito, primarily Aedes aegypti and, lesser, Ae. albopictus. Dengue virus is a ...

Immune-Mediated Pathogenesis in Dengue Virus Infection - MDPI

In this review, we discuss known mechanisms of DENV-mediated immunopathogenesis and its association with disease progression and severity.

Molecular Insight into Dengue Virus Pathogenesis and Its ...

DENV infection is detected by host pattern recognition receptors that selectively bind viral RNA molecules, including TLRs and RIG-I-like receptors (RLRs).

Molecular pathogenesis of dengue virus infection in Aedes ...

Deciphering the molecular interactions between DENV and its vector is a promising field to develop such efficient control strategies.

Dengue virus: pathogenesis and potential for small molecule inhibitors

Several potential small-molecule inhibitors like efavirenz, tipranavir and dasabuvir have been tested against envelope and non-structural proteins of DENV.

Dengue infection | Nature Reviews Disease Primers

Four main factors control dengue virus (DENV) disease response along a response continuum: immune status, virus strain, genetic status and age.

Medline ® Abstract for Reference 63 of 'Dengue virus infection

As both cell tropism and tissue tropism of DENV are considered major determinants in the pathogenesis of dengue, there is a critical need for adequate tropism ...

Dengue Virus Pathogenesis: an Integrated View - ASM Journals

The pathogenesis of DHF and DSS involves viral virulence factors and detrimental host responses, collectively resulting in abnormal hemostasis and increased ...

Virology , Pathogenesis and Laboratory Diagnosis of Dengue

➢ 46 samples (fever<8 days) that were NS1 and/or IgM positive were selected for dengue virus serotyping. ➢ Dengue viral RNA could be detected in 27 samples ( ...

New Perspectives on Dengue Pathogenesis - SciELO

The virus spreads through the lymphatic system. As a result of the first viremia, a population of mononuclear descent cells are obtained, such as monocytes, ...

Dengue virus: epidemiology, biology, and disease aetiology

A positive-stranded enveloped RNA virus (DENV) is principally transmitted by Aedes mosquitoes. It has four antigenically distinct serotypes, DENV-1 to DENV-4, ...

Dengue Virus Pathogenesis: an Integrated View

More than 50 years of research on dengue has resulted in a host of literature, which strongly suggests that the pathogenesis of DHF and DSS involves viral ...