Development of Lupus|like Autoimmune Diseases by Disruption of ...

Development of lupus-like autoimmune diseases by disruption of the ...

Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity. 1999 Aug;11(2):141-51.

Development of Lupus-like Autoimmune Diseases by Disruption of ...

In the present study, we report that PD-1-deficient B6 mice spontaneously developed typical lupus-like glomerulonephritis and destructive arthritis as they age, ...

Development of Lupus-like Autoimmune Diseases by ... - CORE

disease manifestations, although none of these celerated by introduction of a Fas mutation (lpr). susceptible genes have been identified to date (re-.

Development of Lupus-like Autoimmune Diseases by Disruption of ...

/ Development of Lupus-like Autoimmune Diseases by Disruption of the PD-1 Gene Encoding an ITIM Motif-Carrying Immunoreceptor · Locations · Bioscience, Natural ...

Development of Lupus-like Autoimmune Diseases by Disruption of ...

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Systemic lupus erythematosus - Autoimmunity - NCBI Bookshelf

Systemic lupus erythematosus (SLE) is an autoimmune, multisystemic disease which may affect virtually any organ in the body and encompass a wide spectrum of ...

How Lupus Affects the Immune System

The production of autoantibodies in people with lupus and other autoimmune diseases causes the immune system to target the body's own cells for destruction. For ...

Development of Lupus-like Autoimmune Diseases by Disruption of ...

Development of Lupus-like Autoimmune Diseases by Disruption of the PD-1 Gene Encoding an ITIM Motif-Carrying Immunoreceptor · List of references · Publications ...

Disease Development - Autoimmune Disease

Three factors are at play in the pathogenesis of autoimmune diseases: genes, immune system, and the environment where the patient lives.

Pathogenesis of autoimmune disease | Nature Reviews Nephrology

B and/or T cell reactivity signifies a disturbance of immune tolerance and is essential to the development of autoimmunity. The extent of these ...

Lupus - Symptoms & causes - Mayo Clinic

As an autoimmune disease, lupus occurs when your immune system attacks healthy tissue in your body. It's likely that lupus results from a combination of ...

Systemic lupus erythematosus - Genetics - MedlinePlus

Systemic lupus erythematosus (SLE) is a chronic disease that ... About a third of people with SLE develop kidney disease (nephritis).

A breakthrough for lupus treatment? Study explores CAR T-cell ...

Lupus, formally known as Systemic lupus erythematosus (SLE), is a chronic autoimmune disorder that occurs when the body's own defenses, the ...

Development of lupus-like autoimmune diseases by disruption of the ...

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Autoimmune disorders: MedlinePlus Medical Encyclopedia

The exact cause of autoimmune disorders is unknown. One theory is that some microorganisms (such as bacteria or viruses) or drugs may trigger ...

Autoimmune Disease: Why Is My Immune System Attacking Itself?

For example, having a family member with lupus or multiple sclerosis (MS) raises your risk of getting these diseases. Some families have multiple members ...

Autoimmune Diseases | Boston Children's Hospital

African-American children, for instance, seem to be more likely than Caucasians to develop lupus (SLE) and scleroderma, but the opposite is true of multiple ...

Autoimmune Diseases: Causes, Symptoms, and Treatments - WebMD

Systemic lupus erythematosus (lupus). When you have lupus, you develop autoimmune antibodies that can attach to tissues throughout your body.

What Causes Lupus?

Scientists aren't sure what exactly causes lupus. But most believe it's a combination of genes, hormones, and environment.

Systemic Lupus Erythematosus (SLE) - Medscape Reference

Although the specific cause of SLE is unknown, multiple factors are associated with the development of the disease, including genetic, ...