Development of novel agents based on nitric oxide for the control of ...

Development of novel agents based on nitric oxide for the control of colon cancer ... Acta Pharmacol Sin. 2007 Sep;28(9):1429-33. doi: 10.1111/j.1745-7254.2007.

Nitric oxide-donating nonsteroidal anti-inflammatory drugs (NO-NSAIDs) represent a novel class of compounds that hold promise as agents for ...

Development of novel agents based on nitric oxide for the control of ...

Development of novel agents based on nitric oxide for the control of colon cancer1. Vassiliki Kozoni2, Theophilos Rosenberg3, Basil Rigas2,4. 2 Division of ...

[PDF] Development of novel agents based on nitric oxide for the ...

The mechanism of action of NO-NSAIDs involves the modulation of several critical cellular signaling pathways, whereas the induction of a state of oxidative ...

Novel agents for cancer prevention based on nitric oxide - PubMed

Abstract. NO (nitric oxide) biology has provided the impetus for the development of anticancer agents based on their ability to release NO. NO-NSAIDs ...

Synthesis of novel furozan-based nitric oxide-releasing derivatives ...

Aim. To search for novel nitric oxide (NO) releasing anti-tumor agents, a series of furoxan-based nitric oxide-releasing derivatives of 1 ...

Development of novel agents based on nitric oxide for the control of ...

Development of novel agents based on nitric oxide for the control of colon cancer. https://doi.org/10.1111/j.1745-7254.2007.00696.x · Full text. Journal: Acta ...

Development of novel nitric oxide production inhibitors based on the ...

Nitric oxide (NO), the smallest signaling molecule known, can be excessively produced by overexpressed inducible nitric oxide synthase ...

Development of a novel nitric oxide (NO) production inhibitor with ...

Research paper. Development of a novel nitric oxide (NO) production inhibitor with potential therapeutic effect on chronic inflammation.

Recent Developments in Nitric Oxide Donors and Delivery ... - MDPI

The use of nitric oxide (NO) is emerging as a promising, novel approach for the treatment of antibiotic resistant bacteria and biofilm infections. Depending ...

Design, Synthesis, and Investigation of Novel Nitric Oxide (NO) - MDPI

In a proof-of-concept study, we successfully incorporated nitrate ester groups onto two previously studied potent antisickling aromatic aldehydes.

Nitric oxide donors and cardiovascular agents modulating the ...

Several NO donors have been used in clinical settings for decades (eg, nitroglycerin and nitroprusside). However, the growth of interest in the ...

Recent developments in nitric oxide donor drugs - Miller - 2007

In 1992, the free radical, nitric oxide (formula •N=O, abbreviated to NO), was awarded the curious accolade of 'molecule of the year' () and the ...

Nitric Oxide (NO)-Releasing Macromolecules: Rational Design and ...

Indeed, some of them are clinically used for the treatment of diseases such as sodium nitroprusside and nitroglycerin (Nichols et al., 2012). In the past 20 ...

Nitroglycerin and Nitric Oxide — A Rondo of Themes in ...

Other novel aspects of the chemistry of nitric oxide, such as its ability to modify cysteinyl groups post-translationally to form S- ...

Design of Selective Neuronal Nitric Oxide Synthase Inhibitors for the ...

Nitric oxide (NO), which is produced from l-arginine by the nitric oxide synthase (NOS) family of enzymes, is an important second-messenger molecule that ...

Discovery of Dual Inducible/Neuronal Nitric Oxide Synthase (iNOS ...

), dimeric enzymes that catalyze the formation of nitric oxide (NO) from arginine, have been identified. (1) Of the three isoforms, iNOS and nNOS are closely ...

(PDF) Application of nitric oxide in drug discovery and development

Introduction: It is becoming increasingly clear that many diseases are characterized or associated with perturbations in nitric oxide (NO) ...

Nitric oxide and cancer: a review | World Journal of Surgical Oncology

Over past decades, NO has emerged as a molecule of interest in carcinogenesis and tumor growth progression. However, there is considerable ...

Novel Agents Targeting Nitric Oxide - Bentham Science Publisher

Nitric oxide (NO) is a soluble gas continuously synthesized from the amino acid L-arginine in endothelial cells by the constitutive ...