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Dexmedetomidine vs Midazolam or Propofol for ...


Dexmedetomidine vs Midazolam or Propofol for Sedation During ...

Dexmedetomidine may enhance patient safety and comfort in long-term sedation. It reduced the incidence of coma and delirium when compared with ...

Dexmedetomidine vs midazolam or propofol for sedation ... - PubMed

Dexmedetomidine reduced duration of mechanical ventilation compared with midazolam and improved patients' ability to communicate pain compared ...

A comparation of dexmedetomidine and midazolam for sedation in ...

In conclusion, combined with evidence from recent studies, it suggests that dexmedetomidine is comparable to midazolam in sedation, with lower ...

MIDEX-PRODEX - The Bottom Line

Dexmedetomidine is non-inferior to midazolam and propofol for long-term mild to moderate sedation on intensive care. It may reduce time to ...

Dexmedetomidine or Propofol for Sedation in Mechanically ...

We found no difference between dexmedetomidine and propofol in the number of days alive without delirium or coma (adjusted median, 10.7 vs. 10.8 ...

Outcomes of dexmedetomidine versus propofol sedation in critically ...

Dexmedetomidine did not significantly impact ICU length of stay compared with propofol, but it significantly reduced the duration of mechanical ventilation and ...

Dexmedetomidine vs Midazolam or Propofol for ...

The MIDEX trial compared midazolam with dexmedetomidine in ICUs of 44 centers in 9 European countries; the PRODEX trial compared propofol with ...

Comparative Effectiveness of Midazolam, Propofol, and ... - Frontiers

In general, our findings indicate that dexmedetomidine may be superior to midazolam or propofol. There are multiple mechanisms by which ...

Dexmedetomidine vs Midazolam for Sedation of Critically Ill Patients

There was no difference in the primary efficacy outcome, percentage of time within the target RASS range (77.3% for dexmedetomidine-treated ...

Outcomes of dexmedetomidine versus propofol sedation in critically ...

Dexmedetomidine did not significantly impact ICU length of stay compared with propofol, but it significantly reduced the duration of mechanical ventilation and ...

Dexmedetomidine versus midazolam and propofol for sedation in ...

Dexmedetomidine was significantly related to lower mortality when compared with midazolam and propofol. Midazolam had a comparably higher mortality than ...

Dexmedetomidine vs. Propofol for Sedation During Mechanical ...

Compared with propofol and benzodiazepines, dexmedetomidine has been associated with less delirium and lighter sedation in small studies.

MIDEX-PRODEX - Wiki Journal Club

Dexmedetomidine was non-inferior to midazolam or propofol in maintaining target sedation levels and also offered the perquisite of improving the patient's ...

Cost-Minimization Analysis of Dexmedetomidine Compared to ...

Dexmedetomidine, propofol, and midazolam are commonly used in the intensive care unit (ICU) to sedate mechanically ventilated patients in the United States.

Comparison of dexmedetomidine, midazolam, and propofol as an ...

The endoscopist satisfaction level was significantly higher in dexmedetomidine group as compared to propofol and midazolam (60%, 56.7%, 13.3%;.

Brain protective effect of dexmedetomidine vs propofol for sedation ...

Dexmedetomidine and propofol are two sedatives used for long-term sedation. It remains unclear whether dexmedetomidine provides superior ...

Safety and efficacy of dexmedetomidine vs ketamine vs midazolam ...

This study aimed to compare the effects of these drugs in combination with propofol among cancer patients undergoing GI endoscopy.

Differences in efficacy and safety of midazolam vs ...

These results demonstrated that dexmedetomidine could reduce the duration of ICU stay and extubation, suggesting that dexmedetomidine ...

Dexmedetomidine versus standard care sedation with propofol or ...

Dexmedetomidine was shown in two European randomized double-blind double-dummy trials (PRODEX and MIDEX) to be non-inferior to propofol and ...

Effect of dexmedetomidine vs midazolam vs propofol on cytokines ...

Abstract: Objective: To compare the effects of total intravenous anesthesia (TIVA) with midazolam, propofol or dex- medetomidine on the cytokine production ...