Dexmedetomidine vs Midazolam or Propofol for Sedation During ...

Dexmedetomidine may enhance patient safety and comfort in long-term sedation. It reduced the incidence of coma and delirium when compared with ...

Dexmedetomidine vs midazolam or propofol for sedation ... - PubMed

Dexmedetomidine reduced duration of mechanical ventilation compared with midazolam and improved patients' ability to communicate pain compared with midazolam ...

MIDEX-PRODEX - The Bottom Line

Dexmedetomidine is non-inferior to midazolam and propofol for long-term mild to moderate sedation on intensive care. It may reduce time to ...

Dexmedetomidine or Propofol for Sedation in Mechanically ...

We found no difference between dexmedetomidine and propofol in the number of days alive without delirium or coma (adjusted median, 10.7 vs. 10.8 ...

A comparation of dexmedetomidine and midazolam for sedation in ...

Some previous analysis suggested that dexmedetomidine provided an advantage over midazolam in terms of shorter sedation duration and fewer ...

Dexmedetomidine vs Midazolam or Propofol for ...

Context Long-term sedation with midazolam or propofol in intensive care units (ICUs) has serious adverse effects. Dexmedetomidine, an ␣2-agonist ...

Outcomes of dexmedetomidine versus propofol sedation in critically ...

Our analyses across specific ICU patient types also found no significant difference. However, across cardiac surgical patients, dexmedetomidine ...

Dexmedetomidine vs Midazolam for Sedation of Critically Ill Patients

Sedation Efficacy. There was no difference in the primary efficacy outcome, percentage of time within the target RASS range (77.3% for ...

Dexmedetomidine versus midazolam and propofol for sedation in ...

Dexmedetomidine was significantly related to lower mortality when compared with midazolam and propofol. Midazolam had a comparably higher mortality than ...

Dexmedetomidine vs. Propofol for Sedation During Mechanical ...

Compared with propofol and benzodiazepines, dexmedetomidine has been associated with less delirium and lighter sedation in small studies.

Outcomes of dexmedetomidine versus propofol sedation in critically ...

Dexmedetomidine did not significantly impact ICU length of stay compared with propofol, but it significantly reduced the duration of mechanical ventilation and ...

Dexmedetomidine vs midazolam or pr - H1 Connect

The results of these two studies suggest that dexmedetomidine is not inferior to propofol or midazolam for the long-term sedation of mechanically ventilated ...

MIDEX-PRODEX - Wiki Journal Club

Dexmedetomidine was non-inferior to midazolam or propofol in maintaining target sedation levels and also offered the perquisite of improving the patient's ...

Comparative Effectiveness of Midazolam, Propofol, and ... - Frontiers

Sedation with dexmedetomidine was associated with a lower in-hospital mortality rate than sedation with midazolam and propofol or sedation without ...

Dexmedetomidine vs Midazolam or Propofol for Sedation During ...

PDF | Long-term sedation with midazolam or propofol in intensive care units (ICUs) has serious adverse effects. Dexmedetomidine ...

Safety and efficacy of dexmedetomidine vs ketamine vs midazolam ...

Moreover, comparable findings were observed by Yin et al. [Citation24]. They found that in comparison to propofol-dexmedetomidine, the ...

Dexmedetomidine versus propofol/midazolam for long-term ...

In a small uncontrolled series, dexmedetomidine infused continuously for up to 7 days was an effective sedative and analgesic-sparing drug [12].

Dexmedetomidine and Propofol Sedation in Critically Ill Patients and ...

Conclusions: In patients ⩽65 years of age sedated with dexmedetomidine and propofol combination, preferentially increasing the dose of propofol ...

Efficacy of dexmedetomidine compared with midazolam for sedation ...

The sedative benefits of dexmedetomidine vs midazolam remain inconclusive. While some secondary outcomes showed clinical effectiveness of dexmedetomidine, more ...

Sequential use of midazolam and dexmedetomidine for long-term ...

Current sedatives have different side-effect profiles and remain problematic in long-term sedation [4]. Midazolam and propofol used to be the ...