Diagnostic and Therapeutic Implications of Long Non|Coding RNAs ...

Diagnostic and Therapeutic Implications of Long Non-Coding RNAs ...

Recent studies have indicated that numerous regulatory RNAs, such as long non-coding RNAs (lncRNAs), have a role in tumor initiation and progression. When it ...

Diagnostic and Therapeutic Implications of Long Non-Coding RNAs ...

Recent studies have indicated that numerous regulatory RNAs, such as long non-coding RNAs (lncRNAs), have a role in tumor initiation and ...

Long Non-coding RNAs in Cancer: Implications for Diagnosis ...

Due to the large number of lncRNAs, with an estimate of 102,000, lncRNA-based research holds great promise in cancer treatment (3, 4). LncRNAs ...

The prognostic, diagnostic, and therapeutic impact of Long ...

Long non-coding RNAs (lncRNAs) emerge as valuable treasured targets for cancer prognosis, diagnosis, and therapy, given their high specificity, convenient non- ...

Long Non-Coding RNAs in Diagnosis, Treatment, Prognosis, and ...

While most studies reported oncogenic effects for MALAT1, TUG1, and NEAT1, there are some controversies regarding these lncRNAs. Expression levels of lncRNAs ...

Gene regulation by long non-coding RNAs and its biological functions

Evidence accumulated over the past decade shows that long non-coding RNAs (lncRNAs) are widely expressed and have key roles in gene regulation.

Article The long non-coding RNAs, a new cancer diagnostic and ...

(b) LncRNA-based therapies may target the lncRNA by utilizing RNA interference (RNAi) therapeutic molecule and/or use small molecular inhibitors of their ...

Long non-coding RNAs towards precision medicine in gastric cancer

Long non-coding RNAs (lncRNAs) in body fluids have attracted widespread attention as biomarkers for early screening, diagnosis, treatment, prognosis, and ...

Long non-coding RNAs: implications in targeted diagnoses ...

Other lncRNAs have been associated with drug resistance to standard BC treatment. Examples include ARA-lncRNA (adriamycin resistance associated) ...

significance of long non-coding RNAs in the pathogenesis ...

Long non-coding RNAs (lncRNAs) are transcripts with more than 200 nucleotides in length that have potential protein-coding functions. LncRNAs play important ...

Long Non-Coding RNAs in Neuroblastoma - MDPI

Research conducted in the past decade has shown that long non-coding RNAs, once thought to be transcriptomic noise, play key roles in cancer development.

Emerging potential value of long non-coding RNAs as biomarkers ...

In this study, 160 articles were reviewed, and lncRNAs associated with PC diagnosis, prognosis, and treatment were identified independently. Furthermore, the ...

Long non‑coding RNAs in lung cancer: Regulation patterns, biologic ...

Emerging research has demonstrated that long non‐coding RNAs (lncRNAs), a key genomic product, are commonly dysregulated in lung cancer.

Strategies to target long non-coding RNAs in cancer treatment

Long non-coding RNAs are important regulators of gene expression and diverse biological processes. Their aberrant expression contributes to ...

Non-coding RNAs in cardiovascular diseases - Oxford Academic

Beyond their application as diagnostic and prognostic biomarkers (Section 'Non-coding RNAs as biomarkers'), ncRNA can also be the targets (e.g. miRs, lncRNAs) ...

Long non-coding RNAs: Biogenesis, functions, and ... - Cell Press

and molecular mechanisms of lncRNAs and highlight their clinical significance in the diagnosis and treatment of GC to provide in-depth insights into the ...

Diagnostic and Therapeutic Implications of Long Non-Coding RNAs ...

These markers have been used in diagnosis, risk-stratification and targeted therapy application. Recent studies have indicated that numerous regulatory RNAs, ...

Non-coding RNAs in human health and disease: potential function ...

Long noncoding RNAs (lncRNAs) and microRNAs (miRNAs), as well as other types of non-coding RNAs (ncRNAs), are intriguing targets for therapeutic ...

The Clinical Significance of Long Non-Coding RNAs in Cancer

The diverse involvement of lncRNAs in a variety of cellular processes makes them promising targets for cancer therapy, either through the ...

Noncoding RNA therapeutics — challenges and potential solutions

Therapeutic targeting of noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), represents an attractive ...