Disclosing the role of XBP1s in Alzheimer's disease

Disclosing the role of XBP1s in Alzheimer's disease - Cell Press

Dendritic spines in alzheimer's disease: how the actin cytoskeleton contributes to synaptic failure

Disclosing the role of XBP1s in Alzheimer's disease - PubMed

Beyond the unfolded protein response: Disclosing the role of XBP1s in Alzheimer's disease.

Disclosing the role of XBP1s in Alzheimer's disease

Considering the relevance of UPR in the control of cellular homeostasis, the IRE1a/. XBP1 axis is a promising pharmaceutical candidate for several disorders, ...

The unfolded protein response transcription factor XBP1s ...

The unfolded protein response transcription factor XBP1s ameliorates Alzheimer's disease by improving synaptic function and proteostasis.

The unfolded protein response transcription factor XBP1s ... - PubMed

The unfolded protein response transcription factor XBP1s ameliorates Alzheimer's disease by improving synaptic function and proteostasis.

Disclosing the role of XBP1s in Alzheimer's disease - OUCI

List of references · Duran-Aniotz, The unfolded protein response transcription factor XBP1s ameliorates Alzheimer's disease by improving synaptic function and ...

Beyond the unfolded protein response: Disclosing the role of XBP1s ...

This review briefly documents various aspects of the biology of the transcription factor XBP-1 (X-box Binding Protein-1) and summarizes recent ...

Disclosing the role of XBP1s in Alzheimer's disease

Beyond the unfolded protein response: Disclosing the role of XBP1s in Alzheimer's disease-article.

Beyond the unfolded protein response: Disclosing the role of XBP1s ...

In the last 25 years, neuroscientists in search of a cure for Alzheimer's disease (AD) have devoted their efforts to developing therapeutic strategies ...

Beyond the unfolded protein response: Disclosing the role of XBP1s ...

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alzheimer Disease Limits: Humans Language: En Journal: Mol Ther Journal subject: ...

The unfolded protein response transcription factor XBP1s ...

Request PDF | The unfolded protein response transcription factor XBP1s ameliorates Alzheimer's disease by improving synaptic function and proteostasis ...

The transcription factor XBP1s restores hippocampal synaptic ...

Neuronal network dysfunction and cognitive decline constitute the most prominent features of Alzheimer's disease (AD), although mechanisms ...

Early and Late Chaperone Intervention Therapy ... - Aging Biology

... XBP1s and ADAM10, Restores Proteostasis, and Rescues Learning in Alzheimer's Disease Mice ... The role of tau in Alzheimer's disease and related disorders . CNS ...

Unfolded protein response IRE1/XBP1 signaling is required for ...

XBP1s gene delivery to aged mice can revert brain dysfunction at the morphological, electrophysiological, molecular, and behavioral level. •.

Early and late chaperone intervention therapy boosts XBP1s and ...

Western analyses did not reveal an obvious deficit in BDNF ... The role of CREB and. BDNF in neurobiology and treatment of Alzheimer's disease.

The unfolded protein response transcription factor XBP1s ameliorates

Alzheimer's disease by improving synaptic function and proteostasis. 2. 3. Running title: Overexpression of XBP1s ameliorates Alzheimer's pathology. 4. 5.

The unfolded protein response transcription factor XBP1s ... - OUCI

The unfolded protein response transcription factor XBP1s ameliorates Alzheimer's disease by improving synaptic function and proteostasis ... Authors: Claudia ...

The Transcription Factor XBP1 in Memory and Cognition

Indeed, XBP1 activates a plethora of target genes involved in a variety of physiological functions, including neuronal plasticity (19,24–26), ...

Endoplasmic reticulum unfolded protein response transcriptional ...

Pathological tau disrupts protein homeostasis (proteostasis) within neurons in Alzheimer's disease (AD) and related disorders.

Early and late chaperone intervention therapy boosts XBP1s and ...

Two distinct phenotypes of AD are deficits in cognition and proteostasis, including chronic activation of the unfolded protein response (UPR) ...