Discontinuing disease|modifying multiple sclerosis therapies

Discontinuing disease-modifying multiple sclerosis therapies

Risk of new disease activity in patients with multiple sclerosis who continue or discontinue disease-modifying therapies (DISCOMS): a multicentre, randomised, ...

Disease-Modifying Therapy Discontinuation in Multiple Sclerosis

The goal of disease-modifying therapies (DMTs) is to prevent accumulation of multiple sclerosis (MS) lesions, decrease relapse activity, and lessen overall ...

Navigating the discontinuation of multiple sclerosis first line treatments

This study provides insights into the outcomes of MS patients discontinuing injectable DMTs, emphasizing the importance of age at ...

Discontinuing Disease-Modifying Therapies in Multiple Sclerosis

Over the course of multiple sclerosis, there may come a point where the risks of disease-modifying therapies outweigh the benefits.

Stopping Disease-Modifying Therapy in Nonrelapsing Multiple ...

The DMTs can be stopped safely in older patients with MS (≥7 decades) with no evidence of acute disease for 2 years or longer, with an almost 90% probability ...

Impact of discontinuing disease-modifying therapies on health care ...

This study revealed that DMT discontinuation was associated with higher health care services utilization among midlife patients with MS, ...

Safety of Discontinuing Disease-modifying Therapy in Aging MS ...

Several studies have suggested stopping DMT may be safe in patients over 55 years old with at least two years without active relapses.

Discontinuation of Disease-Modifying Therapy in Multiple Sclerosis

The discontinuation of natalizumab or fingolimod (and by extension, perhaps, siponimod and ozanimod) without adequate substitution of a ...

Comparing Stopping or Continuing Use of Disease Modifying ...

Disease modifying therapies, or DMTs, are medicines that help prevent or reduce relapses among patients with MS. But many older patients with MS don't have ...

Discontinuing Multiple Sclerosis Therapies at Age 55 or Older

Retrospective data suggest that some people with multiple sclerosis (MS) may safely stop disease-modifying therapy (DMT) if stable by a certain ...

For Older Patients With Multiple Sclerosis, Discontinuing Disease ...

Discontinuing disease-modifying therapy (DMT) for multiple sclerosis (MS) appears to be a reasonable option for older patients with no relapses or MRI activity.

Discontinuation of first-line disease-modifying therapy in relapse ...

It is not known if and when first-line disease modifying therapy (DMT) can safely be discontinued in relapse onset multiple sclerosis (MS) patients.

Defining Benign/Burnt-Out MS and Discontinuing Disease-Modifying ...

The study provides Class IV evidence that DMTs can be safely discontinued in older patients with suspected benign/burnt-out MS.

Discontinuation of disease-modifying therapy in MS patients over 60 ...

We aimed to compare baseline differences and clinical outcomes between DMT discontinuers and continuers in a cohort of MS patients older than 60 years.

De-escalation and Discontinuation of Disease-Modifying Therapies ...

The field of multiple sclerosis (MS) has experienced enormous advances in the last 30 years, exemplified by the introduction of over 20 disease- ...

Monitoring, Switching, and Stopping Multiple Sclerosis Disease ...

Someone diagnosed with MS more than 45 years ago and without recent disease activity is unlikely to benefit from any currently available disease-modifying ...

Discontinuation of disease modifying therapies is associated with ...

After DMT discontinuation, 53 previously stable MS patients (32.9%) experienced disability worsening/progression (DWP). 29.2 and 40% of previously stable RRMS ...

Perspectives of individuals with multiple sclerosis on discontinuation ...

The first disease-modifying therapy (DMT) for multiple sclerosis (MS) was approved by the Food and Drug Administration (FDA) in 1993. Since then ...

Treatment Switching and Discontinuation Over 20 Years in the Big ...

Background: Although over a dozen disease modifying treatments (DMTs) are available for relapsing forms of multiple sclerosis (MS), treatment interruption, ...

Older Adults Stopping their MS Therapy | National MS Society

Among 259 adults with MS over age 55, there was no significant difference in the number of participants who had a relapse or new disease ...