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Discovery of biomimetic transamination as a general synthetic ...


Discovery of biomimetic transamination as a general synthetic ...

In this perspective review article, we describe the discovery of azomethine-azomethine isomerization of fluorinated N-benzyl-imines and its further development.

(PDF) Discovery of biomimetic transamination as a general synthetic ...

The biomimetic transamination of fluorinated carbonyl compounds, represent the most methodologically concise and generalized approach to the ...

(PDF) Discovery of biomimetic transamination as a general synthetic ...

Discovery of biomimetic transamination as a general synthetic method for preparation of fluorine-containing amines and amino acids · Abstract and ...

Discovery of biomimetic transamination as a general synthetic ...

... ID: 271299212. Discovery of biomimetic transamination as a general synthetic method for preparation of fluorine-containing amines and amino acids. @article ...

Discovery of biomimetic transamination as a general synthetic ...

Discovery of biomimetic transamination as a general synthetic method for preparation of fluorine-containing amines and amino acids.

New synthetic opportunities for biomimetic transamination

The exciting synthetic aspects of this finding are demonstrated by the improved procedure for transamination of certain fluoroalkyl carbonyl compounds ...

Asymmetric biomimetic transamination of α-keto amides to peptides

Peptides are important compounds with broad applications in many areas. Asymmetric transamination of α-keto amides can provide an efficient ...

Optimization of a Biomimetic Transamination Reaction

For a range of protein substrates, N-terminal transamination offers a convenient way to install a reactive ketone or aldehyde functional ...

Biomimetic asymmetric transamination reactions catalyzed by axial ...

The detailed mechanism of biomimetic asymmetric transamination reaction has been disclosed. ... Quantitative AIM analysis has been utilized to discover the origin ...

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A. Wzorek, “Discovery of biomimetic transamination as a general synthetic method for preparation of fluorine-containing amines and amino acids”, ...

Prebiotic access to enantioenriched amino acids via peptide ... - PNAS

Our work suggests that modern biological transamination may have evolved from a prebiotic half-reaction in reverse, effecting a kinetic resolution of racemic ...

Biomimetic Synthesis and Chemical Proteomics Reveal the ...

... general requirement for the growth of most cancer cell lines. (L) ... Proteome-wide covalent ligand discovery in native biological systems. Nature ...

BIOMIMETIC TRANSAMINATION OF ALPHA -ALKYL BETA -KETO ...

Discovery of biomimetic transamination as a general synthetic method for preparation of fluorine-containing amines and amino acids · Chemistry. Ukr. Bioorg. Acta ...

Prebiotic access to enantioenriched amino acids via peptide - PNAS

... α- keto acids and PM in the context of stereoselective transamination (20,. 21). Shi reported a biomimetic synthetic protocol for the enan-.

The Industrial Age of Biocatalytic Transamination - Fuchs - 2015

The review gives an overview of the application of ω-transaminases in organic synthesis with a focus on active pharmaceutical ingredients (APIs) ...

Biomimetic enantioselective synthesis of β,β-difluoro-α-amino acid ...

However, in the current situation, it is urgent to develop a general ... Biomimetic transamination - a metal-free alternative to the reductive ...

A Practical Synthesis of 5-Aroyl-1-aryltetrazoles Using an Ugi-Like 4 ...

A Practical Synthesis of 5-Aroyl-1-aryltetrazoles Using an Ugi-Like 4-Component Reaction Followed by a Biomimetic Transamination ... general synthesis for this ...

Asymmetric biomimetic transamination of α-keto amides to peptides

AbstractPeptides are important compounds with broad applications in many areas. Asymmetric transamination of α-keto amides can provide an efficient strategy ...

Progress in asymmetric biomimetic transamination of carbonyl ...

Various biomimetic transamination systems have been developed for carbonyl compounds including α-keto acid derivatives, fluoroalkyl ketones, and ...

Transamination and transamidation - SpringerLink

Adler, E., G. · Albaum, H. G., and P. P. Cohen: Transamination and protein synthesis in germinating oat seedlings. · Bessman, S. P., J. · Bonner, J.: Plant ...