- Disruption of C. elegans embryonic P granules upon dlc|1🔍
- DLC|1 facilitates germ granule assembly in Caenorhabditis elegans ...🔍
- C. elegans germ granules sculpt both germline and somatic RNAome🔍
- Segregation of germ granules in living Caenorhabditis elegans ...🔍
- Expansion microscopy reveals subdomains in C. elegans germ ...🔍
- The P Granules of C. elegans🔍
- Compartmentalized localization of perinuclear proteins within germ ...🔍
- C. elegans germ granules require both assembly and localized ...🔍
Disruption of C. elegans embryonic P granules upon dlc|1
Disruption of C. elegans embryonic P granules upon dlc-1(RNAi) is ...
elegans embryo as loss of dlc-1 disrupts embryonic P granules in vivo (Figure 1A-D) and (Day et al. 2022). DLC-1 is a light chain component of ...
DLC-1 facilitates germ granule assembly in Caenorhabditis elegans ...
Asymmetric assembly of embryonic P granules requires the presence of multiple core components: phase separation of PGL proteins is disrupted in meg-3/meg-4 ...
Disruption of C. elegans embryonic P granules upon dlc-1(RNAi) is ...
Disruption of C. elegans embryonic P granules upon dlc-1(RNAi) is not associated with P granule component loss. Authors, Mary Ellenbecker , Ekaterina Voronina.
C. elegans germ granules sculpt both germline and somatic RNAome
Specifically, P granules contain RNA binding protein PGL-1, Piwi proteins (known as PRG-1 in C. elegans) and piRNAs (Piwi-interacting RNAs). Z ...
Segregation of germ granules in living Caenorhabditis elegans ...
P1 then divides unequally to produce the somatic daughter EMS on the ventral-anterior side and the germline daughter P2 at the posterior pole of the embryo (Fig ...
Expansion microscopy reveals subdomains in C. elegans germ ...
... 1 (Piwi-related gene-1), which binds piRNAs, is localized to the P granule (Batista et al, 2008). Furthermore, disruption of P granules in ...
The P Granules of C. elegans: A Genetic Model for the Study of RNA ...
P granules are RNA/protein condensates in the germline of Caenorhabditis elegans. Genetic analyses have begun to identify the proteins that regulate P granule ...
Compartmentalized localization of perinuclear proteins within germ ...
P granule assembly and function in Caenorhabditis elegans germ cells. ... 1 on 21U and 26G RNAs in the germline of Caenorhabditis elegans.
C. elegans germ granules require both assembly and localized ...
Here we analyze a key P granule scaffolding protein, PGL-1, to investigate the functional relationship between P granule assembly and function.
dlc-1 is required for embryonic P granule integrity. (A-D)...
Disruption of C. elegans embryonic P granules upon dlc-1(RNAi) is not ... 1 and FBF-2 in Caenorhabditis elegans germline stem and progenitor cells.
Article par-1, a gene required for establishing polarity in C. elegans ...
Brief cytochalasin-induced disruption of microfilaments during a critical interval in 1-cell C. ... granules in embryos, larvae, and adults of Caenorhabditis ...
PAR-2 is asymmetrically distributed and promotes association of P ...
... P granules and PAR-1 with the cortex in C. elegans embryos. Lynn Boyd,. Lynn ... S. (. 1990. ). Brief cytochalasin-induced disruption of microfilaments during a ...
P granules extend the nuclear pore complex environment in the C ...
elegans embryos (Fig. 3). For comparison of GLH-1 to a bona fide NPC component, we tested NPP-4. After expression of the NPP-4 FG ...
Germline P Granules Are Liquid Droplets That Localize by ... - Science
In Caenorhabditis elegans, the germ granules are called P granules. P ... Upon symmetry breaking, the embryo polarizes along the anterior-posterior ...
Disruption of P granules by RNAi or by deficiency for pgl-1 results in...
on Empty Vector (EV) or P granule RNAi at 25 °C were scored for sterility, embryonic lethality, or fertility; n = 16–30 worms per condition, two independent ...
Local thermodynamics govern formation and dissolution of ... - PNAS
We were able to observe up to five cycles of dissolution and condensation showing that the formation of P granules in the C. elegans embryo is reversible over ...
The Vasa-like protein RDE-12 associates with WAGO-1 in P granules and is ... Germ-granule components prevent somatic development in the C. elegans ...
POS-1 and germ cell specification
1. Embryonic development of C. elegans. An abbreviated lineage diagram is shown on the left. Diagrams of embryos at corresponding stages are shown on ...
PLK-1 Regulation of Asymmetric Cell Division in the Early ... - Frontiers
In this review, we focus on the role of PLK-1 during the asymmetric division of the one-cell C. elegans embryo (zygote). We describe the mechanisms by which PLK ...
Robust spatiotemporal organization of mitotic events in ... - Cell Press
1. Gonczy, P. ∙ Rose, L.S.. Polarity Establishment, Asymmetric Division and Segregation of Fate Determinants in Early c. elegans Embryos.