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Distinct Selectivity of Gangliosides Required for CD4


Distinct selectivity of gangliosides required for CD4⁺ T and CD8⁺ T ...

Molecules called gangliosides are known to be major components of lipid rafts, but their role in T-cell activation remains to be elucidated. This review ...

Distinct selectivity of gangliosides required for CD4 + T and CD8 + T ...

CD4T cells require a-series gangliosides for activation. •. CD8T cells require o-series gangliosides for activation. •. GM3 synthase null mice ...

Distinct selectivity of gangliosides required for CD4 + T and CD8 + T ...

Molecules called gangliosides are known to be major components of lipid rafts, but their role in T-cell activation remains to be elucidated. This review ...

CD4 and CD8 T cells require different membrane gangliosides for ...

While investigating T-cell activation in ganglioside-deficient mice, we observed that CD4 + and CD8 + T cells required different ganglioside subsets for ...

Distinct selectivity of gangliosides required for CD4+ T and CD8+ T ...

This review summarizes recent findings that different types of T cells require distinct ganglioside types for the activation. Control of ganglioside expression ...

[PDF] Distinct selectivity of gangliosides required for CD4⁺ T and ...

Semantic Scholar extracted view of "Distinct selectivity of gangliosides required for CD4⁺ T and CD8⁺ T cell activation." by J. Inokuchi et al.

Gangliosides induce selective modulation of CD4 from helper T ...

The activity of gangliosides appeared to require both ... different monoclonal antibodies specific for a variety of different CD4 epitopes.

Distinct requirement of ganglioside species on CD4⁺ T and CD8⁺ T ...

Download scientific diagram | Distinct requirement of ganglioside species on CD4⁺ T and CD8⁺ T cell activation ... selective and specific to individual cells, ...

Gangliosides in T Cell Immunity - SpringerLink

Polarization of the ganglioside GM1 occurs only in CD4+ T cells after TCR clustering. In addition, GM1 and GM3 gangliosides define different types of raft ...

CD4 and CD8 T cells require different membrane gangliosides for ...

Distinct expression patterns of ganglioside species in CD4(+) T and CD8(+) T cells, perhaps in uniquely functional lipid rafts, define immune functions in each ...

The Role of Glycosphingolipids in Immune Cell Functions - Frontiers

CD4 and CD8 T cells require different membrane gangliosides for activation. ... Distinct selectivity of gangliosides required for CD4(+) T and CD8(+) T cell ...

gangliosides in membrane organization - AIR Unimi

different cellular subpopulations requires the expression of distinct ganglioside ... Distinct selectivity of gangliosides required for CD4(+) T and CD8(+) T cell ...

Distinct selectivity of gangliosides required for CD4 T and CD8 T cell ...

Distinct selectivity of gangliosides required for CD4 + T and CD8 + Tcell activation ☆Jin-ichi Inokuchia, ⁎ , Masakazu Nagafuku a , Isao Ohno b , Akemi ...

The biological role and immunotherapy of gangliosides and GD3 ...

CD4 and CD8 T cells require different membrane gangliosides for activation. Proc. Natl. Acad. Sci. U. S. A. 109 (6), E336–E342. doi:10.1073/pnas.1114965109.

The regulatory roles of glycosphingolipid‐enriched lipid rafts in ...

In contrast, a-series and o-series gangliosides form distinct rafts on CD4+ and CD8+ T cell subsets, respectively, contributing to the ...

Two Distinct T Cell Subsets, CD4 + and CD8 + CD60 + , and Their ...

It is well recognized that CD4+ T cells and their cytokines (IL-4 and IL-13) are required for induction of human and murine IgE responses in vivo and in vitro ( ...

CD38 in SLE CD4 T cells promotes Ca 2+ flux and suppresses ...

... selective SIRT1 inhibitor, EX527. Flow cytometry analysis ... CD4 and CD8 T cells require different membrane gangliosides for activation.

enriched lipid rafts in immune systems

Distinct selectivity of gangliosides required for CD4(+). T and CD8 ... (2012) CD4 and CD8 T cells require different membrane gangliosides for.

The Abundance and Availability of Cytokine Receptor IL-2Rβ ...

... CD4 T cells because of their selective expression of ThPOK. However, ThPOK ... CD4 and CD8 T cells require different membrane gangliosides for activation.

Modulation of CD4 Th Cell Differentiation by Ganglioside GD1a In ...

... selective differentiating pressures of DC1-inducing pertussis toxin (PT) and DC2 ... Thus, ganglioside exposure of DC impairs, by at least two distinct ...