Diversity in genetic risk of recurrent stroke

Diversity in genetic risk of recurrent stroke: a genome-wide ...

This article is part of the Research Topic Diversity in Stroke Omic(s) and Epidemiology Research: Opportunities and Challenges

Diversity in genetic risk of recurrent stroke: a genome-wide ...

Substantial recurrent stroke risk disparities exist among ancestral groups. Notably, Africans face double the risk and higher fatality rates.

Table_1_Diversity in genetic risk of recurrent stroke: a genome-wide ...

Recurrent strokes are seven times more lethal than initial ones, with 54% leading to long-term disability. Substantial recurrent stroke risk ...

Genetic risk factors for ischaemic stroke and its subtypes (the ...

Two loci associated with atrial fibrillation (PITX2 and ZFHX3) were associated with cardioembolic stroke, whereas a locus on chromosome 9p21 ...

Stroke genetics informs drug discovery and risk prediction across ...

On the basis of internal cross-ancestry validation and an independent follow-up in 89,084 additional cases of stroke (30% non-European) and ...

Family History and Risk of Recurrent Stroke - AHA Journals

In addition, in a systematic review of twin studies that investigated the genetic epidemiology of stroke, it was noted that monozygotic twins ...

OPUS at UTS: Diversity in genetic risk of recurrent stroke

Recurrent strokes are seven times more lethal than initial ones, with 54% leading to long-term disability. Substantial recurrent stroke risk disparities exist ...

Diversity in genetic risk of recurrent stroke: a genome-wide ... - DOAJ

Recurrent strokes are seven times more lethal than initial ones, with 54% leading to long-term disability. Substantial recurrent stroke risk disparities exist ...

Racial Disparities in Stroke Recurrence - Neurology.org

At younger ages, Black race was more strongly associated with recurrence, and this effect may not be fully attenuated by traditional stroke risk factors.

Stroke Risk Factors, Genetics, and Prevention | Circulation Research

Recent research also suggests that common and rare genetic polymorphisms can influence risk of more common causes of stroke, due to both other ...

Genetics in Ischemic Stroke: Current Perspectives and Future ...

Ischemic stroke is a heterogeneous condition influenced by a combination of genetic, environmental, and lifestyle-related risk factors. A family history of ...

Racial differences in recurrent ischemic stroke risk ... - Neurology.org

The risk of stroke recurrence among older Americans hospitalized for ischemic stroke is higher for blacks compared to whites, while 30-day case fatality after ...

Genetic risk, incident stroke, and the benefits of adhering ... - The BMJ

The risk of incident stroke was 35% higher among those at high genetic risk (top third of polygenic score) compared with those at low genetic ...

Genes, neighborhoods and a surprising finding on stroke risk

A genetic score may be able to identify higher stroke risk – but only for people living in the most privileged neighborhoods, ...

Genetics of ischemic stroke functional outcome | Journal of Neurology

The known variants span diverse biological systems and are related to inflammation, vascular homeostasis, growth factors, metabolism, the p53 ...

Diversity in genetic risk of recurrent stroke - SciLifeLab Publications

Diversity in genetic risk of recurrent stroke: a genome-wide association study meta-analysis. JSON. Aldridge CM, Armstrong ND, Sunmonu NA, Becker C ...

Genetic and Genomic Epidemiology of Stroke in People of African ...

Stroke is a complex and heterogeneous disease. Risk of stroke involves the interplay between genetic, epigenetic, and environmental factors. Stroke is the ...

Association of Vascular Risk Factors and Genetic ... - JAMA Network

Several monogenic disorders are associated with stroke and vascular dementia. These predominantly cause lacunar stroke. The most common of these ...

Subtyping in ischemic stroke genetic research - ScienceDirect.com

Discovery of genes that influence stroke risk might be facilitated if phenotypic heterogeneity of the population studied were reduced by studying individual ...

UVA Researchers Lead $3.2 Million Study to Identify Unique and ...

Nearly one quarter of annual stroke events are recurrent attacks that are likely to be more disabling or fatal. This study will focus on the ...