Do you cap cisplatin dose in obese patients undergoing

Do you cap cisplatin dose in obese patients undergoing - theMednet

Do you cap cisplatin dose in obese patients undergoing chemotherapy in germ cell tumors? Do you cap BSA at 2 or 2.2 for such patients to prevent Cisplatin ...

Appropriate Systemic Therapy Dosing for Obese Adult Patients With ...

In the event of toxicity, the consensus of the Panel is that dose modifications of systemic antineoplastic therapies should be handled similarly ...

Dosing considerations for obese patients receiving cancer ... - PubMed

Data suggest an increased dose of carboplatin, cisplatin, ifosfamide, paclitaxel, and vincristine may be needed in obese patients.

Appropriate Chemotherapy Dosing for Obese Adult Patients With ...

There is no evidence that short- or long-term toxicity is increased among obese patients receiving full weight–based chemotherapy doses. Most data indicate that ...

Dosing Chemotherapy in Obese Patients, Still Not Answered

At the same time, a growing body of evidence suggests that chemotherapy dosing in obese patients based on actual body weight is not associated with increased ...

Conditioning Chemotherapy Dose Adjustment in Obese Patients

Dose on ABW25 in adults (obese and nonobese) receiving per kilogram dosing or BSA based on TBW for m2 dosing. All regimens >12 mg/kg PO equivalent are ...

Obesity and chemotherapy administration: between empiric and ...

Practice pattern studies demonstrate that up to 40% of obese patients receive limited doses that are not based on actual body weight [Citation18]. In routine ...

Antineoplastic dosing in overweight and obese cancer patients

This is however often not the case since BMI and BSA are not informative on body composition as they fail to distinguish between fat and lean ...

Chemotherapy dose reductions in obese patients with colorectal ...

In cancer patients with a large Body Surface Area, chemotherapy drug doses are often reduced, as studies have suggested that their pharmacokinetics may be ...

4CPS-114 Dosing of platinum and taxanes in obese patients

For carboplatin, depending on the GFR obtained, this should be limited to a maximum of 150 mL/min or use of an adjusted body weight for dosing. Furthermore ...

Dosing for Obesity New Chemotherapy Guidelines Linked to Body ...

“We gave examples of patients who are obese and what the dose would be for some common regimens like doxorubicin for breast cancer or R-CHOP for ...

Dosing chemotherapy in obese patients: Actual versus assigned ...

Based upon the current clinical data of obesity and chemotherapy dosing it can be concluded there is very limited if any data to support the perception that ...

Obesity and chemotherapy administration: between empiric and ...

in obese patients are arbitrarily capped ... effects of dose reduction in obese stage III colon cancer patients undergoing adjuvant chemotherapy.

Appropriate Chemotherapy Dosing for Obese Adult Patients With ...

There are insufficient data for addressing dosing for overweight and obese patients receiving targeted ... How should I dose for the patient with ...

Dosing Chemotherapy in Obese Patients: No Clear Answers, Yet

Should we cap doses? Overdosing patients is a concern for all clinicians ... 17 This retrospective analysis involves overweight patients receiving carboplatin.

Higher rate of severe toxicities in obese patients receiving dose ...

In routine clinical practice, chemotherapy doses are frequently capped at a body surface area (BSA) of 2.0m2 or adjusted to an ideal weight for obese patients ...

BSA values should be determined using only the Mosteller equation ...

Which body surface area calculation equation should be used to prevent incidence of incorrect dosing of chemotherapy? Calculation of Doses in Obese Patients. 2.

Conditioning Chemotherapy Dose Adjustment in Obese Patients

Dosing: dosed on TBW at admission unless patient was >15 kg above IBW; then they were dosed on adjusted body weight (40%), ABW40. Patients were compared based ...

Guidelines on Chemotherapy Dosing in Obese Adult Patients

It should however be noted that there was limited inclusion of transplant literature in the ASCO 2012 guideline and chemotherapy doses used in transplant ...

Dosing of chemotherapy in obese and cachectic patients

Six hospitals did not respond, because they did ... comes in endometrial cancer patients receiving doxorubicin and cisplatin: a Gynecologic ...