Drug Repurposing
Drug Repurposing: An Effective Tool in Modern Drug Discovery - PMC
Repurposing helps overcome antibiotic resistance. For example, TB strains resistant to currently used drug combinations are found in all parts ...
Drug repurposing: progress, challenges and recommendations
Drug repurposing — a strategy for identifying new uses for approved or investigational drugs that are outside the scope of the original ...
Drug repurposing: approaches, methods and considerations - Elsevier
Drug repurposing, also called drug repositioning or drug reprofiling, is the identification of new therapeutic uses for existing or investigational drugs.
Drug Repositioning - an overview | ScienceDirect Topics
Drug Repositioning. Drug repositioning or drug repurposing is a widely used strategy that seeks to identify new targets for drugs that are already approved for ...
Drug repositioning - Wikipedia
Drug repositioning ... Drug repositioning (also called drug repurposing) involves the investigation of existing drugs for new therapeutic purposes.
Approved drugs have already been tested in humans, so some repurposed treatments could enter clinical trials much sooner. They also could be approved for new ...
Drug Repurposing Hub | Broad Institute
The Drug Repurposing Hub is one of the most comprehensive and up-to-date biologically annotated collections of FDA-approved compounds in the world. Researchers ...
Drug Repurposing Strategies, Challenges and Successes
Drug-focused repurposing may expand the application of an existing drug to new indications based on off-label usage, analysis of abandoned drugs ...
A foundation model for clinician-centered drug repurposing - Nature
Here we introduce TxGNN, a graph foundation model for zero-shot drug repurposing, identifying therapeutic candidates even for diseases with limited treatment ...
Drug Repositioning - an overview | ScienceDirect Topics
Drug repurposing (DR), also known as drug repositioning or re-profiling, is an approach to identify new therapeutic indications (other than original ...
CURE Drug Repurposing Collaboratory - Critical Path Institute
CDRC is designed to capture real-world clinical outcome data to advance drug repurposing and inform future clinical trials for diseases of high unmet medical ...
Drug repurposing for rare: progress and opportunities for ... - Frontiers
Repurposing is one of the key opportunities to address the unmet rare diseases therapeutic need. Based on cases of drug repurposing in small ...
Drug repurposing or repositioning? The language matters | STAT
“Drug repositioning” refer only to non-FDA-approved compounds that could be developed to treat a disease other than the one for which they were originally ...
R&D Trends: Maximizing dark data to enhance drug repurposing
By structuring information in a custom knowledge management system, companies can convert their dark data into smart information assets for ...
Drug repurposing: Misconceptions, challenges, and opportunities for ...
This Review discusses factors critical for the successful launch of a repurposed medicine and is designed to help academic investigators better identify drug ...
The CSTL is partnering with Every Cure to pioneer novel approaches to rapidly identifying and advancing drug repurposing opportunities.
Drug Repurposing Strategy (DRS): Emerging Approach to Identify ...
This review focuses on drug repurposing strategy applied for existing drugs including Remdesivir, Favipiravir, Ribavirin, Baraticinib, Tocilizumab, Chloroquine ...
Drug Repurposing for Rare Diseases - Cell Press
The process of repurposing drugs for new indications, compared with the development of novel orphan drugs, is a time-saving and cost-efficient ...
Drug repurposing: a systematic review on root causes, barriers and ...
Repurposing is a drug development strategy receiving heightened attention after the Food and Drug Administration granted emergency use ...
Drug Repurposing Hub - Broad Institute
Order library plates to screen yourself or collaborate with the Broad Institute's Center for the Development of Therapeutics to see if an existing drug may work ...