Drug delivery strategies for poorly water|soluble drugs

Drug Delivery Strategies for Poorly Water‐Soluble Drugs

Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for ...

Drug delivery strategies for poorly water-soluble drugs - PubMed

Drug delivery strategies for poorly water-soluble drugs. Expert Opin Drug Deliv. 2007 Jul;4(4):403-16. doi: 10.1517/17425247.4.4.403. Authors. Alfred Fahr ...

Drug delivery strategies for poorly water-soluble drugs - PubMed

Drug delivery strategies for poorly water-soluble drugs: the industrial perspective · Abstract · Publication types · MeSH terms · Substances.

Strategies for formulating and delivering poorly water-soluble drugs

Prodrugs represent 10% of worldwide marketed drugs and were 33% of the small active molecules approved in 2008 [15], [16]. Prodrug design represents a versatile ...

Full article: Drug delivery strategies for poorly water-soluble drugs

1. Poorly water-soluble drugs continue to present challenges for oral and parenteral delivery. After oral administration, the degree of ...

[PDF] Drug delivery strategies for poorly water-soluble drugs

Drug delivery strategies for poorly water-soluble drugs · A. Fahr, Xiangli Liu · Published in Expert Opinion on Drug… 1 July 2007 · Medicine, Chemistry, Materials ...

Full article: Drug delivery strategies for poorly water-soluble drugs

In general, the formulations for poorly water-soluble drugs include crystalline solid formulations, amorphous formulations and lipid ...

Strategies for formulating and delivering poorly water-soluble drugs

Strategies for formulating and delivering poorly water-soluble drugs ... Zawilska et al. Prodrugs: a challenge for the drug development. Pharmacol ...

Drug Delivery Strategies for Poorly Water-Soluble Drugs

Request PDF | Drug Delivery Strategies for Poorly Water-Soluble Drugs | The intravenous administration of poorly water-soluble compounds is problematic.

Nanonization strategies for poorly water-soluble drugs

Polymeric micelles offer many pharmaceutical advantages for the delivery of hydrophobic drugs, such as high stability with improved hemocompatibility and drug ...

Drug delivery strategies for poorly water-soluble drugs

Drug Delivery Strategies for Poorly Water-Soluble Drugs is an essential multidisciplinary guide to this important area of drug formulation for ...

A Step towards Bioavailability Enhancement of Poorly Soluble Drugs

Numerous studies have demonstrated that, via a variety of methods, nanoparticles can increase the oral bioavailability of hydrophobic and hydrophilic drugs [83] ...

Drug delivery strategies for poorly water-soluble drugs

Drug delivery strategies for poorly water-soluble drugs ; English · Chichester, West Sussex : John Wiley & Sons, 2012. · Drug Delivery Systems. Chemistry, ...

Drug Delivery Strategies for Poorly Water-Soluble Drugs - Wiley-VCH

Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for administration to patients ...

Drug Delivery Strategies for Poorly Water-Soluble Drugs

Many strategies have been developed to overcome this formulation challenge and these include formulating poorly water soluble drugs into salts, using cosolvents ...

Lipid-based oral formulation in capsules to improve the delivery of ...

Poorly water-soluble drugs demonstrate significant challenge in pharmaceutical development, which is linked to their limited oral bioavailability and ...

Drug delivery strategies for poorly water-soluble drugs. - Abstract

Formulation specialists are confronted with an even higher level of difficulties when these drugs have to be delivered site specifically. This article addresses ...

Strategies in poorly soluble drug delivery systems

This is related to the fact that over 40% of drugs available on the pharmaceutical market are characterized by low solubility in water. Thus, the paper ...

Oral drug delivery strategies for development of poorly water soluble ...

Selecting the appropriate formulation and solubility-enabling technology for poorly water soluble drugs is an essential element in the ...

Drug delivery strategies for poorly water-soluble drugs - Academia.edu

A major hurdle in pharmaceutical formulation is water insolubility of most of drugs affecting their stability and bioavailability. If the drug is also insoluble ...