Durotaxis and negative durotaxis

Durotaxis and negative durotaxis: where should cells go? - Nature

Durotaxis and negative durotaxis are processes in which cell migration is directed by extracellular stiffness. Durotaxis is the tendency of ...

Positive and negative durotaxis – mechanisms and emerging concepts

Types of durotaxis. On stiffness gradients, single cells can exhibit either positive durotaxis (. View largeDownload slide. Types of durotaxis.

Durotaxis and negative durotaxis: where should cells go? - PubMed

Durotaxis and negative durotaxis are processes in which cell migration is directed by extracellular stiffness. Durotaxis is the tendency of ...

Directed cell migration towards softer environments - PubMed

In agreement with this model, negative durotaxis is selectively disrupted and even reversed by the partial inhibition of actomyosin contractility. Conversely, ...

Positive, negative and controlled durotaxis - RSC Publishing

We show that positive and negative durotaxis found across cell types are explained by asymmetries in the cell adhesion dynamics.

Persistent random walks: a unified theory for durotaxis and negative ...

Some cells move preferentially toward stiff matrix (durotaxis), while some cells move preferentially toward soft matrix (negative durotaxis).

Negative durotaxis: cell movement toward softer environments

Although cellular processes can sometimes turn toward softer environments, durotaxis at the level of cells has thus far been observed ...

Durotaxis and negative durotaxis: where should cells go?

Durotaxis is the tendency of cells to migrate toward stiffer areas, while negative durotaxis occurs when cells migrate toward regions with lower ...

Durotaxis: Current Biology - Cell Press

... durotaxis can also be negative (i.e. towards soft regions). Such negative durotaxis occurs during the development of the Xenopus optic ...

Positive, negative and controlled durotaxis - NASA/ADS

Durotaxis is a physical process central to life, including embryogenesis, tissue regeneration, and tumor growth. This work proposes a mechanistic rationale ...

Reviews & Analysis | Communications Biology - Nature

Durotaxis and negative durotaxis: where should cells go? · Congcong Ji · Yuxing Huang.

Positive and negative durotaxis – mechanisms and emerging ...

Cell migration is controlled by the coordinated action of cell adhesion, cytoskeletal dynamics, contractility and cell extrinsic cues.

An elastic-damaging cohesive law for cell-substrate adhesion with ...

However, negative durotaxis has been shown to be related to the existence of a substrate optimal stiffness at which the cell deploys its maximum ...

Mechanisms of durotaxis and negative durotaxis. a Cell migration is...

Right: the ability of cells to migrate from the stiff end to the soft end of the extracellular matrix is called negative durotaxis. b Myosin IIB is unpolarized ...

YAP Activation in Promoting Negative Durotaxis and Acral ... - MDPI

Directed cell migration towards a softer environment is called negative durotaxis. The mechanism and pathological relevance of negative durotaxis in tumor ...

Positive, negative and controlled durotaxis. - Semantic Scholar

It is shown how durotaxis can be engineered to manipulate cell migration, which has important implications in biology, medicine, and bioengineering.

Magazine

Negative durotaxis has been attributed to the capacity of the cell membrane to transduce mechanical signals. Indeed, blocking the ...

Positive and negative durotaxis – mechanisms and emerging concepts

J Cell Sci. REVIEW. 2024. ABSTRACT. Cell migration is controlled by the coordinated action of cell adhesion, cytoskeletal dynamics, ...

Negative durotaxis: cell movement toward softer environments

Aleksi Isomursu, Keun-Young Park, Jay Hou, Bo Cheng, Ghaidan Shamsan, Benjamin Fuller, Jesse Kasim, M. Mohsen Mahmoodi, Tian Jian Lu, Guy M. Genin, Feng Xu, ...

Positive and negative durotaxis - mechanisms and emerging concepts.

Significant conceptual advances that have been made in the appreciation of cell plasticity and context dependency in stiffness-guided directional cell ...