Eeyarestatin I

Eeyarestatin I A cell-permeable oxo-imidazolidinyl-hydroxyurea that localizes to ER, where it interacts with AAA ATPase p97 via its nitrofuran-containing ...

Eeyarestatin I | ERAD Inhibitor - MedchemExpress.com

Eeyarestatin I, a potent endoplasmic reticulum-associated protein degradation (ERAD) inhibitor, is a potent protein translocation inhibitor.

Eeyarestatin 1 (CAS Number: 412960-54-4) | Cayman Chemical

Eeyarestatin 1: An ERAD inhibitor. CAS Number: 412960-54-4. Purity: ≥98%.

Eeyarestatin I Supplier | CAS 412960-54-4 - Tocris Bioscience

View and buy high purity Eeyarestatin I from Tocris Bioscience. Potent inhibitor of ER-associated protein degradation and translocation.

Eeyarestatin I inhibits Sec61-mediated protein translocation at the ...

We now show that the previously identified inhibitor of ER-associated degradation (ERAD) eeyarestatin 1 (ES(I)) is a potent inhibitor of protein ...

Eeyarestatin I (CAS 412960-54-4) - R&D Systems

View and buy high purity Eeyarestatin I. Potent inhibitor of ER-associated protein degradation and translocation. Cited in 6 publications.

Eeyarestatin I, an inhibitor of the valosin-containing protein, exhibits ...

EEY is a strong virucide against two unrelated flaviviruses, encouraging further studies to investigate its potential use as a broad-acting drug.

Eeyarestatin I | 99.07%(HPLC) | In Stock | Others - Selleck Chemicals

Eeyarestatin I is a potent inhibitor of endoplasmic reticulum-associated protein degradation (ERAD). Eeyarestatin I also inhibits Sec61 translocon.

Eeyarestatin I | CAS 412960-54-4 | SCBT - Santa Cruz Biotechnology

Eeyarestatin I, CAS: 412960-54-4, is a potent inhibitor of endoplasmic reticulum associated protein degradation. Cited in 12 publications.

The ERAD Inhibitor Eeyarestatin I Is a Bifunctional Compound with a ...

Our findings reveal a class of bifunctional chemical agents that can preferentially inhibit membrane-bound p97 to disrupt ER homeostasis and to induce tumor ...

Eeyarestatin I (3922) by Tocris, Part of Bio-Techne

Eeyarestatin I : Potent inhibitor of ER-associated protein degradation and translocation. ≥98% (HPLC).

Eeyarestatin Compounds Selectively Enhance Sec61-Mediated ...

Summary. Eeyarestatin 1 (ES1) inhibits p97-dependent protein degradation, Sec61-dependent protein translocation into the endoplasmic reticulum (ER), and ...

Eeyarestatin I - APExBIO

Eeyarestatin I (EerI [1]) is an inhibitor of endoplasmic reticulum-associated degradation (ERAD). It disturbs endoplasmic reticulum (ER) homeostasis and has ...

Eeyarestatin I = 98 HPLC 412960-54-4 - Sigma-Aldrich

Eeyarestatin I ≥98% (HPLC); CAS Number: 412960-54-4; Synonyms: 3-(4-Chlorophenyl)-4-[[[(4-chlorophenyl)amino]carbonyl]hydroxyamino]-5 ...

Eeyarestatin I - VWR

Eeyarestatin I is an inhibitor of the ERAD (Endoplasmic-reticulum -associated protein degradation) pathway, blocking the degradation of misfolded proteins ...

[PDF] The ERAD Inhibitor Eeyarestatin I Is a Bifunctional Compound ...

The findings reveal a class of bifunctional chemical agents that can preferentially inhibit membrane-bound p97 to disrupt ER homeostasis and to induce tumor ...

Inhibition of p97-dependent Protein Degradation by Eeyarestatin I*

In mammalian cells, ERAD can be blocked by a chemical inhibitor termed Eeyarestatin I, but the mechanism of EerI action is unclear. Here we ...

Eeyarestatin I - CAS 412960-54-4 - Calbiochem | 324521

Eeyarestatin I - CAS 412960-54-4 - Calbiochem A cell-permeable oxo-imidazolidinyl-hydroxyurea that localizes to ER, where it interacts with AAA ATPase p97 ...

Eeyarestatin I | ERAD inhibitor | CAS NO.:412960-54-4 - GlpBio

The ERAD inhibitor Eeyarestatin I is a bifunctional compound with a membrane-binding domain and a p97/VCP inhibitory group. PLoS One 5(11), 1-12 (2010). [4].

Dissection of the Dislocation Pathway for Type I Membrane Proteins ...

Eeyarestatin I also inhibited degradation of a second misfolded type I membrane protein, T-cell receptor α. Both compounds stabilize these dislocation ...