Effect of Long|term Incretin|Based Therapies on Ischemic Heart ...

Effect of Long-term Incretin-Based Therapies on Ischemic Heart ...

Patients with type 2 diabetes mellitus (T2DM) experience many cardiovascular complications. Several studies have demonstrated the ...

Effect of Long-term Incretin-Based Therapies on Ischemic ... - PubMed

Patients with type 2 diabetes mellitus (T2DM) experience many cardiovascular complications. Several studies have demonstrated the ...

Cardiovascular Effects of Incretin-Based Therapies - NCBI

GLP-1Ra CVOTs have also demonstrated inconsistencies regarding the secondary outcome of hospitalization for heart failure (HF), whereby the ...

(PDF) Effect of Long-term Incretin-Based Therapies on Ischemic ...

Patients with type 2 diabetes mellitus (T2DM) experience many cardiovascular complications. Several studies have demonstrated the ...

Cardiovascular Actions of Incretin-Based Therapies - AHA Journals

Taken together, GLP-1 and GLP-1R agonists produce favorable effects on cardiac function in animal models of ischemia/reperfusion injury and in ...

Cardiovascular Outcome Trials of the Incretin-Based Therapies

Results: Independent of their glucose-lowering action, incretin-based therapies may have incretin-dependent mechanisms that positively affect blood pressure, ...

The cardiovascular safety of incretin-based therapies: a review of ...

There is mechanistic evidence to suggest that GLP-1 receptor agonists may confer cardioprotective effects following ischaemia. Retrospective ...

Incretins-Based Therapies and Their Cardiovascular Effects - MDPI

Glucagon-like peptide-1 receptor agonists (GLP1-RA) and dipeptidyl peptidase-4 inhibitors (DPP4i) were recently introduced as novel classes of drugs for ...

Incretin‐based therapies for the management of cardiometabolic ...

It also reduced the heart failure composite endpoint (HR: 0.82, 95% CI: 0.71–0.96) and had favorable effects compared to placebo on multiple ...

Incretin-based therapy: a powerful and promising weapon in the ...

The pancreatic effects of GLP-1 receptor agonists include glucose-lowering effects by stimulating insulin secretion and inhibiting glucagon ...

Cardiovascular Actions and Clinical Outcomes With Glucagon-Like ...

It is notable that incretin-based therapies (GLP-1R agonists [GLP-1RAs] and DPP-4Is) exert multiple nonglycemic actions in the cardiovascular ...

Incretin Therapies: Effects Beyond Glycemic Control

In the long term, if these β-cell trophic effects are sustained, the potential exists to possibly reverse or stabilize the disease process. In clinical studies, ...

Incretin-Based Therapy for Diabetes: What a Cardiologist Needs to ...

The weight-loss effects of short-acting versus long-acting agents appear to be comparable (17). It may be reasonable to recommend GLP-1Ra in combination with ...

Cardiovascular Effects of Incretin-Based Therapies

Long-term follow-up data showed no improvement in cardiac function or the clinical outcomes of patients with acute MI receiving the combined therapy (65). It is ...

Cardiovascular Safety of Incretin-Based Therapies in Type 2 Diabetes

Regulatory requirements mandate that new drugs for treatment of patients with type 2 diabetes mellitus (T2DM), such as dipeptidyl ...

Cardiovascular effects of the incretin‐based therapy: the good, the ...

Incretin-based therapy does not increase the risk of cardiovascular events in general. However, the risk of hospital admission for heart failure ...

Achieving equitable access to incretin-based therapies in ...

Incretin hormones are crucial for glucose homeostasis, mediating nutrient absorption and pancreatic hormone secretion. Furthermore, GLP1RAs enhance insulin ...

Effect of PCI on Long-Term Survival in Patients with Stable Ischemic ...

Percutaneous coronary intervention (PCI) relieves angina in patients with stable ischemic heart disease, but clinical trials have not shown ...

Cardiovascular Effects of Incretin-Based Therapies - ResearchGate

... It has been also postulated that GLP1-Ra may exert CV beneficial effects by impacting post-MI cardiac remodeling and ischemia-reperfusion (IR) injury [ ...

Treatment and prognosis of heart failure with preserved ejection ...

However, we do not routinely perform this procedure in patients with HFpEF; a trial that studied the long-term effects of this procedure did not ...