Effect of tumor necrosis factor|alpha antagonism in asthma

Effect of tumor necrosis factor-alpha antagonism in asthma - NCBI

It remains controversial whether tumor necrosis factor (TNF)-α antagonism is effective for asthma. This meta-analysis was performed to evaluate efficacy of ...

Effect of tumor necrosis factor-α antagonism in asthma - PubMed

It remains controversial whether tumor necrosis factor (TNF)-α antagonism is effective for asthma. This meta-analysis was performed to ...

Evidence of a Role of Tumor Necrosis Factor α in Refractory Asthma

Background. The development of tumor necrosis factor α (TNF-α) antagonists has made it feasible to investigate the role of this cytokine in ...

Effect of tumor necrosis factor-α antagonism in asthma - SpringerLink

It remains controversial whether tumor necrosis factor (TNF)-α antagonism is effective for asthma. This meta-analysis was performed to ...

Targeting TNF-a: A novel therapeutic approach for asthma

Effect of tumor necrosis factor antagonism on allergen-mediated asthmatic airway inflammation. Respir Med 2005;99:1175-82. 61. Morjaria JB, Chauhan AJ, Bobu ...

Effect of tumor necrosis factor antagonism on allergen-mediated ...

TNF antagonism may not be effective for preventing allergen-mediated eosinophilic airway inflammation in mild-to-moderate asthmatics. Transient hemiplegia, ...

Effect of tumor necrosis factor antagonism on allergen-mediated ...

To assess whether tumor necrosis factor (TNF) antagonism can attenuate eosinophilic airway inflammation in patients with mild-to-moderate allergic asthma.

Effect of Tumor Necrosis Factor-α Antagonism in Asthma

Effect of Tumor Necrosis Factor-α Antagonism in Asthma: a. Meta-analysis of the Published Literature*. Xiaoju CHEN (陈晓菊)1, 2, Liang XIONG (熊亮)1, Shouming ...

Effect of tumor necrosis factor antagonism on allergen-mediated ...

Conclusions: TNF antagonism may not be effective for preventing allergen- mediated eosinophilic airway inflammation in mild-to-moderate asthmatics. Transient ...

Tumour necrosis factor-α as a therapeutic target in asthma

TNF-α is a multifunctional proinflammatory cytokine whose effects are regulated both by local concentrations and cell surface receptor dynamics.

Effect of tumor necrosis factor-α antagonism in asthma: a meta ...

Evaluated efficacy of TNF-α antagonism in treatment of patients with asthma found it was superior to control chemotherapy in terms of asthma exacerbation, ...

Targeting TNF-α: A novel therapeutic approach for asthma

The development of novel TNF-α antagonists has allowed us to test the role of this cytokine in vivo. Preliminary studies have demonstrated an improvement in ...

Anti-Tumor Necrosis Factor for Supplementary Management in ...

Hence, TNF antagonism might affect the immunomodulation in asthma, thus, rendering the ineffectiveness of this approach in severe asthma. Furthermore, treatment ...

Evidence of a role of tumor necrosis factor alpha in refractory asthma.

Patients with refractory asthma have evidence of up-regulation of the TNF-alpha axis, and treatment with etanercept was associated with a significant ...

Tumor Necrosis Factor Alpha-Mediated Asthma? - Karger Publishers

In addition to the early and late asthmatic responses, Th2-biased airway inflammation leads to airway hyperresponsiveness (AHR) to nonspecific ...

The Effects of a Monoclonal Antibody Directed against Tumor ...

We hypothesize that TNF-α may have a role in maintaining the inflammatory state in patients with asthma (20, 21), and may thus represent a ...

Effect of tumor necrosis factor-α antagonism in asthma: A meta ...

Request PDF | Effect of tumor necrosis factor-α antagonism in asthma: A meta-analysis of the published literature | It remains controversial whether tumor ...

Tumour necrosis factor‐α: The role of this multifunctional cytokine in ...

These data suggest that TNF-α plays a role in the initiation of allergic asthmatic airway inflammation and the generation of airway hyper- ...

TNF-Alpha Antagonism in Severe Asthma? - ResearchGate

Tumour necrosis factor- alpha (TNF-α) is a pro-inflammatory cytokine that has been implicated in many aspects of the airway pathology in asthma. Evidence is ...

Inflammation, Asthma, and Tumor Necrosis Factor-alpha

TNF-alpha also has direct effects on airway reactivity to methacholine or allergen, as shown in isolated tracheal ring experiments. Given these effects of TNF- ...