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Effective Loading Dose of Dexmedetomidine to Induce Adequate ...


Effective Loading Dose of Dexmedetomidine to Induce Adequate ...

The ED50 and ED95 of loading dexmedetomidine to achieve adequate sedation were 0.82 μg kg -1 and 0.96 μg kg -1 for caesarean section under spinal ...

The 95% effective dose of dexmedetomidine to induce adequate ...

The 95% effective dose of dexmedetomidine to induce adequate sedation in patients with chronic insomnia disorder was 1.75 μg/kg.

Effective dose of dexmedetomidine to induce adequate sedation

After spinal anesthesia, the assigned loading dose of dexmedetomidine was infused intravenously for 10 minutes, after which infusion was ...

Effective dose of dexmedetomidine for inducing adequate sedation ...

After spinal anesthesia, patients were randomly allocated into five groups depending on the dexmedetomidine loading dose; 0.1 μg/kg, 0.3 μg/kg, 0.5/g/kg, 0.7/g/ ...

Determination of the effective dose of dexmedetomidine to achieve ...

Results: Through the strategy mentioned, the depth of surgical anesthesia was successfully achieved by DEX-led anesthesia induction. The ED50 and ED95 of the ...

Effective Loading Dose of Dexmedetomidine to Induce Adequate ...

The ED50 and ED95 of loading dexmedetomidine to achieve adequate sedation were 0.82 and 0.96 μg kg-1 for caesarean section under spinal anaesthesia, ...

Median Effective Dose of Dexmedetomidine Inducing Bradycardia in ...

The Dixon and Massay sequential method were applied to determine the loading dose of dexmedetomidine, starting from 1.0 µg/kg. The dose for the ...

Effectiveness of single loading dose of dexmedetomidine combined ...

The single loading dose of dexmedetomidine was set at 0.5 μg/kg at the start of anesthesia induction and loading for 10 min. The primary outcome ...

(PDF) The 95% effective dose of dexmedetomidine to induce ...

Conclusions The 95% effective dose of dexmedetomidine to induce adequate sedation in patients with chronic insomnia disorder was 1.75 µg/kg.

Effective dose of dexmedetomidine to induce adequate sedation in ...

After spinal anesthesia, the assigned loading dose of dexmedetomidine was infused intravenously for 10 minutes, after which infusion was maintained at a rate of ...

PRECEDEX® 100 micrograms/mL Concentrate for Infusion - Medsafe

The use of a loading dose of dexmedetomidine was associated with an increased rate of adverse events, including hypotension, hypertension and bradycardia, in ...

[PDF] Optimal dose of dexmedetomidine for sedation during spinal ...

... sufficient for surgery of less than 60 min, and infusion followed by maintenance dose ( ... The effective dose (ED) of dexmedetomidine to induce an adequate depth ...

Effective dose of dexmedetomidine as an adjuvant sedative to ...

In conclusion, the ED50 for single-dose intravenous dexmedetomidine, which induced adequate sedation in our young-old and middle-old groups ...

Effective dose of dexmedetomidine for inducing adequate sedation ...

After spinal anesthesia, the assigned loading dose of dexmedetomidine was infused intravenously for 10 minutes, after which infusion was maintained at a rate of ...

Comparison of two loading doses of dexmedetomidine for sedation ...

In this study, we compared 0.6 μg/kg of loading dose to 1.0 μg/kg of recommended loading dose for the efficacy and safety in patients during spinal anesthesia.

Sedation with dexmedetomidine in elderly patients during dental ...

One hundred two patients aged 70 to 96 years were presumably appropriately controlled with sedation. DEX was administered at an initial loading ...

Precedex, Igalmi - dexmedetomidine (Rx) - Medscape

... effective dose may be appropriate. butabarbital. butabarbital and ... Preparation of solutions is the same, whether for the loading dose or maintenance infusion ...

Dexmedetomidine - an overview | ScienceDirect Topics

It is administered as a loading dose of 1 μg/kg over 10 to 20 minutes followed by a continuous infusion of 0.2-0.7 μg/kg/hr. Dexmedetomidine has a short ...

Clinical Pharmacokinetics and Pharmacodynamics of ...

The Precedex label specifies a dosing regimen consisting of a 1-µg/kg loading dose in 10 min followed by a maintenance infusion of 0.2–0.7 µg/kg ...

The effects of loading dose administration rate of dexmedetomidine ...

Values are presented as number (%). Group S: a loading dose of dexmedetomidine (DMT) of 0.5 μg/kg over 20 minutes, followed by a continuous ...