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Effective dose of dexmedetomidine for inducing adequate sedation ...


Effective dose of dexmedetomidine to induce adequate sedation in ...

For procedural sedation, a loading dose of 0.5-1.0 µg/kg and a maintenance infusion of 0.2-1.0 µg/kg/h are recommended depending on the ...

The 95% effective dose of dexmedetomidine to induce adequate ...

The 95% effective dose of dexmedetomidine to induce adequate sedation in patients with chronic insomnia disorder: a biased coin design up-and- ...

The 95% effective dose of dexmedetomidine to induce adequate ...

The 95% effective dose of dexmedetomidine to induce adequate sedation in patients with chronic insomnia disorder was 1.75 μg/kg.

Determination of the effective dose of dexmedetomidine to achieve ...

Studies have indicated that DEX-induced deep sedation neurophysiologically approximates non-rapid eye movement (NREM) sleep (5). Anesthesia induction led by DEX ...

Effective dose of dexmedetomidine for inducing adequate sedation ...

Results and discussion: Level of spinal anesthesia, vital signs were not different among groups. Dexmedetomidine ED 50 and ED 95 for the adequate depth of ...

Effective dose of dexmedetomidine to induce adequate sedation in ...

The ED50 and ED95 of dexmedetomidine for adequate sedation were 0.29 µg/kg (95% confidence intervals [CI] 0.14-0.44) and 0.86 µg/kg (95% CI 0.52-1.20), ...

Effective dose of dexmedetomidine as an adjuvant sedative to ...

In conclusion, the ED50 for single-dose intravenous dexmedetomidine, which induced adequate sedation in our young-old and middle-old groups ...

The median effective doses of dexmedetomidine to induce adequate ...

After 20 min of dexmedetomidine injection, adequate sedation was defines as observer′s assessment of alertness/sedation score (OAA/S score) ≤ 3 scores. The ED50 ...

Median Effective Dose of Dexmedetomidine Inducing Bradycardia in ...

Dexmedetomidine is a potent and highly selective α2-adrenoceptor agonist displaying anxiolytic, sedative, sympatholytic, and analgesic effects ...

(PDF) The 95% effective dose of dexmedetomidine to induce ...

Conclusions The 95% effective dose of dexmedetomidine to induce adequate sedation in patients with chronic insomnia disorder was 1.75 µg/kg.

Effective Loading Dose of Dexmedetomidine to Induce Adequate ...

The ED50 and ED95 of loading dexmedetomidine to achieve adequate sedation were 0.82 and 0.96 μg kg-1 for caesarean section under spinal anaesthesia, ...

Insomnia Disorders | The 95% effective dose of dexmedetomidine to ...

Conclusions. The 95% effective dose of dexmedetomidine to induce adequate sedation in patients with chronic insomnia disorder was 1.75 µg/kg.

Adequate sedation with single-dose dexmedetomidine in patients ...

anesthesia. The purpose of this study was to determine the 50% effective dose (ED50) of single-dose DMT to induce adequate light sedation in ...

Precedex, Igalmi - dexmedetomidine (Rx) - Medscape

... effective dose may be appropriate. butabarbital. butabarbital and dexmedetomidine both increase sedation. Use Caution/Monitor. butalbital. butalbital and ...

Dexmedetomidine - an overview | ScienceDirect Topics

Intranasal dosing is 1 to 2 μg/kg administered 30 minutes before induction, producing an observer's assessment alertness/sedation scale of 2 (responds only ...

PRECEDEX® 100 micrograms/mL Concentrate for Infusion - Medsafe

PRECEDEX is only to be used for procedural sedation with the provision of appropriate ... doses within the recommended dose range (0.2-0.7 mcg/kg/hr). The ...

Dose Comparison of Dexmedetomidine Sedation following Spinal ...

The ED50 of dexmedetomidine for adequate sedation in parturient patients was 1.58 μg/kg (1.51–1.66 μg/kg); in nonpregnant women, it was 0.96 μg/ ...

[PDF] Optimal dose of dexmedetomidine for sedation during spinal ...

The loading dose (1 µg/kg/10 min) of dexmedetomidine was sufficient for surgery of less than 60 min, and infusion followed by maintenance dose (0.2 µg ...

Dexmedetomidine: a magic bullet on its way into palliative care—a ...

Dexmedetomidine induces sedation mimicking deep natural sleep via the locus coeruleus. Unlike other hypnotics and sedatives, these patients are ...

Age-Specific Dose Regimens of Dexmedetomidine for Pediatric

These results indicated that dexmedetomidine was effective as a sedative in pediatric patients. ... First, dexmedetomidine alone achieved adequate sedation levels ...