Effects of ramipril on cardiovascular and microvascular outcomes in ...

Ramipril was beneficial for cardiovascular events and overt nephropathy in people with diabetes. The cardiovascular benefit was greater than that ...

Ramipril lowered the risk of the combined primary outcome by 25% (95% Cl 12–36, p=0·0004), myocardial infarction by 22% (6–36), stroke by 33% (10–50), ...

Effects of ramipril on cardiovascular and microvascular outcomes in ...

Background Diabetes mellitus is a strong risk factor for cardiovascular and renal disease. We investigated whether the angiotensin-converting-enzyme (ACE) ...

Effects of ramipril on cardiovascular and microvascular outcomes in ...

Ramipril significantly lowered the risk of major cardiovascular outcomes by 25–30% in a broad range of high-risk middle-aged and elderly people with diabetes ...

effects of ramipril on cardiovascular and microvascular outcomes in ...

The Heart Outcomes Prevention Evaluation (HOPE) Study Investigators. Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes ...

Reduction of cardiovascular events and microvascular ... - PubMed

Use of a composite measure of microvascular complications also suggested a protective effect of ramipril treatment. An interesting finding in the HOPE study is ...

Long-Term Effects of Ramipril on Cardiovascular Events and on ...

Additional reductions in myocardial infarction, revascularization, and the development of diabetes were observed during the follow-up phase ...

Heart Outcomes Prevention Evaluation (HOPE) Investigators: Effects ...

Kaplan-Meier curves show a significantly lower rate of each of the primary outcome endpoints in the ramipril group. The combined primary outcome relative risk ...

Effects of ramipril on cardiovascular and microvascular outcomes in ...

Semantic Scholar extracted view of "Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE ...

Effects of ramipril on cardiovascular and microvascular outcomes in ...

Ramipril lowered the risk of the combined primary outcome by 25% (95% CI 12-36, p=0·0004), myocardial infarction by 22% (6-36), stroke by 33% (10-50), ...

Effects of an Angiotensin-Converting–Enzyme Inhibitor, Ramipril, on ...

Ramipril significantly reduces the rates of death, myocardial infarction, and stroke in a broad range of high-risk patients who are not known to have a low ...

Effects of an Angiotensin-Converting–Enzyme Inhibitor, Ramipril, on ...

The double-blind, two-by-two factorial, randomized Heart Outcomes Prevention Evaluation study evaluated ramipril and vitamin E in 9541 patients.

Effects of ramipril on cardiovascular and microvascular outcomes in ...

Semantic Scholar extracted view of "Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: ...

Medline ® Abstracts for References 39,48 of 'Treatment of ...

Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy. Heart ...

Effects of Ramipril on Coronary Events in High-Risk Persons

Myocardial Infarction and Fatal Acute Ischemic Heart Disease ... During the mean 4.5 years of follow-up, there were 482 (10.4%) patients with ...

Do ACE Inhibitors Provide Protection for Diabetics? - AAFP

The rate of cardiovascular death, stroke or myocardial infarction was significantly lower in the ramipril group than in the placebo group. After ...

Effect of Angiotensin-Converting Enzyme Inhibitors ... - JAMA Network

However, ARB therapy was associated with a 30% reduction in the risk of heart failure. Both ACEIs and ARB agents were not associated with a ...

Effects of ramipril on cardiovascular and microvascular outcomes in ...

Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy. Heart ...

Ramipril and the Development of Diabetes - JAMA Network

Because ramipril reduced the risk of cardiovascular events and diabetic nephropathy, we assessed whether the higher occurrence of these clinical events in ...

Effects of ramipril on cardiovascular and microvascular outcomes in ...

Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy.