Efficacy and safety of incretin therapy in type 2 diabetes

Efficacy and safety of incretin therapy in type 2 diabetes - PubMed

Incretin therapy offers an alternative option to currently available hypoglycemic agents for nonpregnant adults with type 2 diabetes, ...

Efficacy and Safety of Incretin Therapy in Type 2 Diabetes

Incretin therapy offers an alternative option to currently available hypoglycemic agents for nonpregnant adults with type 2 diabetes, with modest efficacy and ...

Efficacy and safety of incretin therapy in type 2 diabetes - NCBI

This review of two new drug classes (glucagon-like peptide 1 analogues and dipeptidyl peptidase 4 inhibitors) concluded that incretin-based therapies offer ...

Efficacy and Safety of Incretin Therapy in Type 2 Diabetes

FEWER THAN HALF OF US ADULTS with type 2 diabetes reach a he- moglobin A1c (HbA1c) level of less than 7% despite several available therapies.1 Ineffective ...

Efficacy and Safety of Incretin-Based Therapies in Patients with Type ...

Incretin-based therapies enhance endogenous insulin secretion without causing hypoglycemia or weight gain. This review focuses on the efficacy ...

Efficacy and Safety of Incretin-Based Therapies in Patients with Type ...

Impairment of incretin activity plays an integral part in the metabolic derangement underlying type 2 diabetes. Glucagon-like peptide–1 (GLP-1) receptor ...

Efficacy and safety of incretin-based therapies: Clinical trial data

In addition to decreasing glycemia in type 2 diabetes, incretin therapies may improve other important parameters, including beta-cell function, blood pressure, ...

Safety and Efficacy of Incretin-Based Therapies in Patients With ...

Eligible studies included randomized controlled trials evaluating incretin-based therapy in adults with type 2 diabetes and estimated glomerular ...

Efficacy and Safety of Incretin-Based Therapies in Patients with Type ...

Additionally, we examine the utility of GLP-1 receptor agonists and DPP-4 inhibitors as these agents may be applied at different stages of type 2 diabetes ...

Efficacy and safety of incretin-based therapies: Clinical trial data

... therapy). Conclusion. In addition to decreasing glycemia in type 2 diabetes, incretin therapies may improve other important parameters, including beta-cell ...

[PDF] Efficacy and safety of incretin therapy in type 2 diabetes

Careful postmarketing surveillance for adverse effects, especially among the DPP4 inhibitors, and continued evaluation in longer-term studies and in ...

All of the incretin-related therapies appear to be well suited for use in elderly populations, with no additional safety considerations directly ...

Efficacy and Safety of Incretin Therapy in Type 2 Diabetes

Incretins lowered hemoglobin A(1c) compared with placebo (weighted mean difference, -0.97% [95% confidence interval {CI}, -1.13% to -0.81%] for GLP-1 analogues ...

Efficacy and Safety of Incretin-Based Therapies in Patients with Type ...

3 Exenatide is available in the United States; it is indicated for adjunctive therapy to improve glycemic con- trol in patients with type 2 diabetes that is ...

Efficacy and Safety of GLP-1 Medicines for Type 2 Diabetes and ...

The hemoglobin A1c (HbA1c) reduction and weight loss were greater with semaglutide relative to therapy with dulaglutide (6). Superior reduction ...

Safety and Efficacy of Incretin-Based Therapies in Patients With ...

INDEX WORDS: Type 2 diabetes mellitus (T2DM); chronic kidney disease (CKD); systematic review; epidemiology; meta-analysis; pharmacoepidemiology ...

Incretin based treatments and mortality in patients with type 2 diabetes

Our systematic review and meta-analysis provides no support for the hypothesis that incretin based treatment is associated with increased ...

Cardiovascular Safety of Incretin-Based Therapies in Type 2 Diabetes

Regulatory requirements mandate that new drugs for treatment of patients with type 2 diabetes mellitus (T2DM), such as dipeptidyl ...

Incretin-Based Therapies in Type 2 Diabetes Mellitus

Exenatide (synthetic exendin-4) is the only GLP-1R agonist approved by regulatory agencies as an adjunct therapy to patients with T2DM not achieving ...

Efficacy and safety of incretin therapy in type 2 diabetes

, Efficacy and safety of incretin therapy in type 2 diabetes: systematic review and meta-analysis. ;; Pittas, Anastassios G E ;, ISSN: 0098-7484 , 1538-3598 ;, ...