Efficacy and safety of trabectedin or dacarbazine for the treatment of ...

Efficacy and Safety of Trabectedin or Dacarbazine for Metastatic ...

The final analysis of PFS, performed after 329 PFS events, showed that treatment with trabectedin resulted in a 45% reduction in the risk of ...

Results of a Phase III Randomized Multicenter Clinical Trial - PubMed

In the final analysis of PFS, trabectedin administration resulted in a 45% reduction in the risk of disease progression or death compared with ...

Efficacy and Safety of Trabectedin or Dacarbazine in Patients with ...

Of patients receiving trabectedin, 75% were treated as outpatients compared with 99% of patients receiving dacarbazine. Prolonged treatment ...

Efficacy and safety of trabectedin or dacarbazine for the treatment of ...

Conclusions: Among patients with uterine LMS, treatment with trabectedin resulted in superior disease control, with significantly longer PFS compared with ...

Results of a Phase III Randomized Multicenter Clinical Trial

In the final analysis of PFS, trabectedin administration resulted in a 45% reduction in the risk of disease progression or death compared with dacarbazine ( ...

Efficacy and Safety of Trabectedin or Dacarbazine for Metastatic ...

Treatment in the metastatic setting includes anthracycline-based chemotherapy or gemcitabine-based chemotherapy. Overall, prognosis is poor and treatment ...

Efficacy and safety of trabectedin or dacarbazine in patients with ...

In this post hoc subset analysis of patients with uLMS who had received prior anthracycline therapy, trabectedin treatment resulted in significantly longer PFS ...

Efficacy and Safety of Trabectedin or Dacarbazine for Treatment of ...

Efficacy and Safety of Trabectedin or Dacarbazine for. Treatment of Patients with Uterine Leiomyosarcoma after Prior Chemotherapy: A Subgroup Analysis. Martee ...

Efficacy and safety of trabectedin or dacarbazine for metastatic ...

Conclusion: Trabectedin demonstrates superior disease control versus conventional dacarbazine in patients who have advanced liposarcoma and ...

Efficacy and safety of trabectedin or dacarbazine in patients with ...

Trabectedin significantly improved progression-free survival vs dacarbazine.•Lack of cumulative toxicity with trabectedin allows for prolonged treatment.

[PDF] Efficacy and Safety of Trabectedin or Dacarbazine for ...

Because disease control in advanced sarcomas is a clinically relevant end point, this study supports the activity of trabectedin for patients with these ...

Efficacy and Safety of Trabectedin or Dacarbazine for Metastatic ...

Trabectedin demonstrates superior disease control versus conventional dacarbazine in patients who have advanced liposarcoma and leiomyosarcoma after they ...

Efficacy and safety of trabectedin for patients with unresectable and ...

The median number of treatment cycles was 3 (range, 1-24). Patients received a median dose intensity of 0.33 mg/m2/wk (range, 0.13-0.41 mg/m2/wk) ...

Assessment of Safety and Efficacy of Combined Trabectedin and ...

First-line systemic treatment for metastatic soft-tissue sarcomas (STSs) has hardly improved over 40 years, doxorubicin being the standard ...

Efficacy and tolerability of trabectedin in elderly patients with sarcoma

Elderly patients treated with trabectedin showed significantly improved PFS [4.9 versus 1.5months, respectively; hazard ratio (HR)=0.40; P=0.0002] but no ...

A subgroup analysis of the randomized phase 3 SAR-3007 study

Efficacy and safety of trabectedin or dacarbazine for the treatment of patients with uterine leiomyosarcoma after prior chemotherapy: A subgroup analysis of ...

Efficacy and safety of trabectedin in metastatic uterine leiomyosarcoma

dacarbazine in patients with unresectable, locally advanced or metastatic liposarcoma or leiomyosarcoma. Overall, 232 of 577 patients had uLMS and were treated ...

A subgroup analysis of the randomized phase 3 SAR-3007 study

Efficacy and safety of trabectedin or dacarbazine for the treatment of patients with uterine leiomyosarcoma after prior chemotherapy: A ...

Safety and efficacy of trabectedin when administered in the inpatient ...

Of the 378 patients who were treated with trabectedin, 100 (27%) and 277 (73%), respectively, first received trabectedin in the inpatient and ...

A Study of Trabectedin or Dacarbazine for the Treatment of Patients ...

A Study of Trabectedin or Dacarbazine for the Treatment of Patients With Advanced Liposarcoma or Leiomyosarcoma · Trial Information · Supporting Documentation.