Elamipretide Clinical Studies and Trials

Elamipretide Clinical Studies and Trials - Stealth BioTherapeutics

Programs & Pipeline. Stealth's lead investigational product candidate, elamipretide, is a peptide compound that readily penetrates cell membranes, and targets ...

Efficacy and Safety of Elamipretide in Individuals With Primary ...

Study Design and Participants. MMPOWER-3 was a 24-week , randomized, double-blind, parallel-group, placebo-controlled clinical trial for adults with PMM ...

Randomized dose-escalation trial of elamipretide in adults with ...

Mitochondrial disease patients' motivations and barriers to participate in clinical trials. Presented at the UMDF Mitochondrial Medicine 2015 International ...

Efficacy and Safety of Elamipretide in Individuals With Primary ...

... study demonstrated that subcutaneous elamipretide is well-tolerated. Trial Registration Information. Trial registered with clinicaltrials.gov, Clinical Trials ...

Elamipretide - Friedreich's Ataxia Research Alliance

... studies with elamipretide ... Elamipretide Clinical Trials. Trials 101 Guide. Improve Mitochondrial Function & Reduce Oxidative Stress. Clinical Trial | Ages 16+ ...

ClinicalTrials.gov NCT03323749

Elamipretide for Adult Patients with Primary Mitochondrial Disease

The clinical trial also involves blood and urine tests, cardiac tests, physical exercise tests, and other study procedures. ... Randomized to receive daily study ...

Phase 1 Clinical Trial of Elamipretide in Intermediate Age-Related ...

Conclusions. Elamipretide appeared to be generally safe and well tolerated in treating intermediate AMD and HRD. Exploratory analyses demonstrate a positive ...

ReCLAIM-2: A Randomized Phase II Clinical Trial Evaluating ...

This study evaluated the safety and efficacy of elamipretide in dry age-related macular degeneration (AMD) with noncentral geographic atrophy (GA). Design.

A phase 2/3 randomized clinical trial followed by an open-label ...

To evaluate effectiveness of elamipretide in Barth syndrome (BTHS), a genetic condition of defects in TAZ, which causes abnormal cardiolipin ...

Randomized dose-escalation trial of elamipretide in adults with ...

Safety and tolerability endpoints included adverse events and changes from baseline in vital signs, ECGs, and clinical laboratory evaluations. Dose escalation ...

tazpower - Barth Syndrome Foundation

Assessment of elamipretide in Barth syndrome - TAZPOWER Clinical Trial ... study evaluating elamipretide in patients with Barth syndrome. The findings ...

Stealth BioTherapeutics enrolls first patient in global Phase 3 clinical ...

In the ReNEW trial, 360 patients will be randomized 2:1 to ... elamipretide in patients with dry AMD in these pivotal Phase 3 trials.

Phase 3 Randomized Trial to Evaluate Subcutaneous Elamipretide ...

... trial that will enrol approximately 130 participants In the whole Clinical Trial. Stealth BioTherapeutics Inc. have begun a study of an investigational drug ...

A Pilot Investigator Initiated Study to Evaluate the Safety, Tolerability ...

Home > Clinical Studies and Trials > A Pilot Investigator Initiated Study to ... Elamipretide in the Treatment of Advanced Symptoms of Friedreich Ataxia (FRDA).

Phase 1 Clinical Trial of Elamipretide in Dry Age-Related Macular ...

Conclusions. Elamipretide seems to be well tolerated without serious AEs in patients with dry AMD and NCGA. Exploratory analyses demonstrated possible positive ...

Stealth BioTherapeutics Announces First Patient Enrolled in Global ...

It has enrolled and dosed its first patient in the ReNEW trial (NCT06373731) as part of its Phase 3 clinical program for elamipretide in patients with dry age- ...

NuPower Study: A Phase 3 Randomized, Double-Blind ... - Orphanet

Homepage > Research and trials > Clinical Trials. Search for a clinical trial ... Elamipretide in Subjects With Primary Mitochondrial Disease Resulting ...

A randomized crossover trial of elamipretide in adults with primary ...

Participants who received a short-course treatment of daily SC elamipretide for 4 weeks experienced a clinically meaningful change in the 6MWT, ...

Despite Failure to Meet End Points, Results of Elamipretide Offer ...

In one of the first phase 3 trials of primary mitochondrial myopathy, elamipretide failed to meet its primary end points; however, ...