Elevating ER

Watch "Elevating ER #1: Why I Started HR Acuity" to discover the inspiration and motivation behind the founding of HR Acuity.

Elevating ER #7: Creating an Insight-Driven Workplace - HR Acuity

Join us for "Elevating ER #7: Creating an Insight-Driven Workplace," part of our engaging web series. This episode focuses on harnessing ...

Elevating ER #8 Why do organizations treat employee risk different ...

Tune in to "Elevating ER #8" to explore why organizations often treat employee risk differently from other resources.

Elevating ER #4 Process & Consistency Drives Employee Experience

My mission for 2020 is to elevate employee relations! I've been working with HR Leaders at Linkedin, Qualcomm, Mastercard and many others on ...

Interrupting synoviolin play at the ER: a plausible action to elevate ...

The role of an endoplasmic reticulum (ER)-resident E3ubiquitin ligase, synoviolin, and its ability to control body weight and energy expenditure.

ER remodeling via lipid metabolism - ScienceDirect.com

However, other studies in different cell lines failed to observe elevated levels of CLIMP63 or other ER-shaping proteins (e.g., RTNs) under ...

Elevated Endoplasmic Reticulum Stress Response Contributes to ...

Treatment of chemical chaperone 4-phenyle-butyric acid alleviated ER stress in adipose tissue stromal cells and adipose tissue macrophages and ...

Impaired autophagy activity is linked to elevated ER-stress and ...

Our results support the notion that diminished autophagy activity with aging contributes to increased adipose tissue ER stress and inflammation.

Elevated ER stress exacerbates dextran sulfate sodium-induced ...

ER-retained peroxiredoxin 4 (PRDX4) protein is highly expressed in the colon. •. PRDX4 localizes to colonic epithelial cells. •. PRDX4-/y mice show ...

ER Stress and Autophagic Perturbations Lead to Elevated ...

ER stress and autophagic perturbations lead to elevated extracellular α-synuclein in GBA-N370S Parkinson's iPSC-derived dopamine neurons.

ER Ca2+ overload activates the IRE1α signaling and promotes cell ...

Normally, the activation of the UPR pathway induced by the accumulation of unfolded proteins in ER leads to the elevation of chaperones in ...

ER stress is not elevated in the 5XFAD mouse model of Alzheimer's ...

Importantly, we did not observe elevation of the ER stress markers p-eIF2α, ATF4, CHOP, p-IRE1α, or BiP at any age in 5XFAD or 5XFAD;BACE1−/− compared with ...

Oxidative and ER stress by elevated insulin biosynthesis and ...

Elevated insulin synthesis partially increased the unfolded protein response, being further potentiated by PA. H2O2 generation caused by elevated insulin ...

A Phase 1b/2, Open-Label, Umbrella Study Evaluating Elacestrant ...

29 ELEVATE: A Phase 1b/2, Open-Label, Umbrella Study Evaluating ... ER+), HER2-Negative (HER2–) Locally Advanced or Metastatic Breast ...

Elevated Endoplasmic Reticulum Stress Response Contributes to ...

Chemical chaperones. ER stress response. Activating Transcription Factor 6. Adipose Tissue. Age Factors. Animals. Cell Culture Techniques. Cytokines.

Abstract PO2-05-04: ELEVATE: A phase 1b/2, open-label, umbrella ...

Background: ER+/HER2- breast cancer (BC) is the most prevalent BC subtype. Endocrine therapy (ET) is the mainstay of treatment; however, ...

Heme scavenging reduces pulmonary endoplasmic reticulum stress ...

Plasma heme and ER stress levels are elevated in patients with very severe COPD and in ferrets exposed to cigarette smoke.

Elevated Endoplasmic Reticulum Stress Response Contributes to ...

Elevated ER stress markers BIP (GRP78), CHOP, cleaved-ATF-6, phospho-IRE1α, and XBP-1 were observed in old compared to young adipose tissue ...

Pneumocytes are distinguished by highly elevated expression of the ...

Pneumocytes are distinguished by highly elevated expression of the ER stress biomarker GRP78, a co-receptor for SARS-CoV-2, in COVID-19 ...

Some ABCA3 mutations elevate ER stress and initiate apoptosis of ...

Our data suggest that expression of partially or completely ER localized ABCA3 mutant proteins can increase the apoptotic cell death of the affected cells.