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Emerging therapies in Ewing sarcoma


Emerging therapies in Ewing sarcoma - PubMed

Close international collaboration between clinicians and biologists will allow us to prioritize promising emerging therapies and develop ...

Emerging therapies in Ewing sarcoma - PMC

The rEECur phase II/III adaptive multiarm trial is the first to compare regimens in a randomized design. To date, four have been evaluated: ...

Emerging therapies in Ewing sarcoma - Current Opinion in Oncology

The study, which randomized 640 patients, demonstrated interval compressed VDC/IE to be more effective and less toxic than its comparator for all stages of ...

ETV6 Could Be Treatment Target for Ewing Sarcoma - NCI

ETV6 Protein Could Be an Important Target for Ewing Sarcoma Treatment ... In Ewing sarcoma cells, ETV6 modulates the behavior of the fusion ...

Groundbreaking trial launches for everyone with Ewing sarcoma

For metastatic patients, regorafenib could be a more effective treatment with fewer potential side effects. “It's important to say that the ...

UCSF Ewing Sarcoma Clinical Trials — San Francisco Bay Area

UCSF has trials for new treatments like a flavored oral drug for kids with recurring tumors and Tegavivint for solid tumors. Genetic testing ...

Ewing sarcoma genomics and recent therapeutic advancements

The current review examined existing and potential experimental therapies that, by enhancing patient survival and quality of life, target multiple signaling ...

Ewing Tumor - Latest on Research & Treatment

Some new drugs that target specific changes in Ewing tumor cells are already being tested. For example, TK216 is a drug that targets the main ...

Effective combination of cold physical plasma and chemotherapy ...

Ewing's sarcoma (ES) is the second most common bone tumor in children and adolescents and is highly malignant. Although the new chemotherapy ...

Ewing Sarcoma Treatment (PDQ®) - NCI

Ewing sarcoma treatment options include multidrug chemotherapy, surgery, and radiation therapy. Treatment approaches titrate therapeutic ...

New Approach to Modeling Ewing Sarcoma Leads to a Novel ...

Researchers find a new pathway that promotes cancer growth and could open the door to targeted therapies.

Consensus recommendations for systemic therapies in the ...

The authors leveraged the expertise assembled by the National Ewing Sarcoma Tumor Board, a multidisciplinary virtual tumor board that meets ...

Emerging therapies in Ewing sarcoma - Research Explorer

There is an unmet need to improve outcomes for patients for Ewing sarcoma, a rare, aggressive sarcoma with a peak incidence in adolescents and young adults ( ...

Towards a new era in the treatment of Ewing sarcoma - The Lancet

Comparison of two chemotherapy regimens in patients with newly diagnosed Ewing sarcoma (EE2012): an open-label, randomised, phase 3 trial

Ewing sarcoma treatment: a gene therapy approach - Nature

The presented studies show that CRISPR technology as a gene editing tool is an excellent technology that promises new possibilities in the ...

Could cancer-killing viruses be a new treatment for Ewing's sarcoma?

The team have found through previous work that oncolytic viruses can kill Ewing's sarcoma cells directly by entering Ewing's sarcoma cells and killing them, or ...

Ewing Sarcoma | Dana-Farber Cancer Institute

Access to the highest quality clinical research and new drugs available for the treatment of Ewing Sarcoma; Support services, including ...

Role of immunotherapy in Ewing sarcoma

These therapies include CAR T cells, monoclonal antibodies (mAbs) and bispecific T cell engagers. In contrast, intracellular targets require presentation of ...

Ewing's Sarcoma Treatment - MD Anderson Cancer Center

Radiation therapy (also called radiotherapy) uses high-energy beams to destroy cancer cells. New radiation therapy techniques and remarkable skill allow ...

Prospects and challenges for the development of new therapies for ...

There is a growing enthusiasm in the Ewing sarcoma community to evaluate poly ADP ribose polymerase (PARP) inhibitors in the clinic. This is the direct result ...