Energy Metabolism in Human Pluripotent Stem Cells and ...

Energy metabolism in human pluripotent stem cells and ... - PubMed

Our results demonstrate that, although the metabolic signature of IPSCs is not identical to that of hESCs, nonetheless they cluster with ...

Measuring energy metabolism in cultured cells, including human ...

Measurements of glycolysis and mitochondrial function are required to quantify energy metabolism in a wide variety of cellular contexts.

Metabolism of human pluripotent stem cells and differentiated cells ...

Utilizing the metabolic features of PSCs and their derivative cells is a promising approach to address these considerations, as metabolic ...

Energy Metabolism in Human Pluripotent Stem and Differentiated ...

We used fibroblasts, human induced PSCs, and human embryonic stem cells to monitor changes in basal metabolic levels according to cell number ...

Energy Metabolism Regulates Stem Cell Pluripotency - Frontiers

This review highlights the roles of the major metabolic pathways in the acquisition and maintenance of the different states of pluripotency.

Pluripotent stem cell energy metabolism: an update - EMBO Press

Abstract. Recent studies link changes in energy metabolism with the fate of pluripotent stem cells (PSCs). Safe use of PSC derivatives in regenerative medicine ...

Energy Metabolism in Human Pluripotent Stem and Differentiated ...

Evaluating cell metabolism is crucial during pluripotent stem cell (PSC) differentiation and somatic cell reprogramming as it affects cell fate.

Regulation of energy metabolism in human pluripotent stem cells

In this review, we will discuss key factors that influence energy metabolism and their association with stem cell functions.

A roadmap for the characterization of energy metabolism in human ...

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) are an increasingly employed model in cardiac research and drug discovery. As cellular ...

OCIAD1 Controls Electron Transport Chain Complex I Activity to ...

Pluripotent stem cells (PSCs) derive energy predominantly from glycolysis and not the energy-efficient oxidative phosphorylation (OXPHOS).

Metabolic switching in pluripotent stem cells reorganizes energy ...

Not only energy generation but also energy usage is significantly reduced in human pluripotent stem cells (hPSCs) due to metabolic switch.

UCP2 regulates energy metabolism and differentiation potential of ...

It has been assumed, based largely on morphologic evidence, that human pluripotent stem cells (hPSCs) contain underdeveloped, ...

Regulation of energy metabolism in human pluripotent stem cells

All living organisms need energy to carry out their essential functions. The importance of energy metabolism is increasingly recognized in human pluripotent ...

UCP2 regulates energy metabolism and differentiation potential of ...

It has been assumed, based largely on morphologic evidence, that human pluripotent stem cells (hPSCs) contain underdeveloped, bioenergetically inactive ...

Energy Metabolism Regulates Stem Cell Pluripotency - Mayo Clinic

Abstract. Pluripotent stem cells (PSCs) are characterized by their unique capacity for both unlimited self-renewal and their potential to ...

Measuring energy metabolism in cultured cells, including human ...

257 Citations · Energy Metabolism in Human Pluripotent Stem and Differentiated Cells Compared Using a Seahorse XF96 Extracellular Flux Analyzer · Assessing the ...

Measuring energy metabolism in cultured cells, including human ...

Measurements of glycolysis and mitochondrial function are required to quantify energy metabolism in a wide variety of cellular contexts. In human ...

Regulation of energy metabolism in human pluripotent stem cells

The importance of energy metabolism is increasingly recognized in human pluripotent stem cells. Energy production is not only essential for cell survival ...

Energy Metabolism Plays a Critical Role in Stem Cell Maintenance ...

Various stem cells gradually turned to be critical players in tissue engineering and regenerative medicine therapies. Current evidence has demonstrated that ...

Metabolism in Human Pluripotent Stem Cells and Cardiomyocytes ...

Downstream of such transcriptional regulatory networks, various stem cell-specific metabolic programs are used to produce energy and metabolites as necessary.